Seth Bordenstein

Affiliate Researcher
Titles and Affiliations
Professor, Biology
Professor, Entomology
Dorothy Foehr Huck and J. Lloyd Huck Endowed Chair in Microbiome Sciences and Director of the Microbiome Center, Huck Institutes of the Life Sciences

In the News

Research Keywords

 These keywords and phrases come from the publications and other research output of this person. See other researchers related to these topics by clicking on any keyword.

Recent Publications

Wolbachia and its pWCP plasmid show differential dynamics during the development of Culex mosquitoes

Brunner, A., Gauliard, C., Tutagata, J., Bordenstein, S. R., Bordenstein, S. R., Trouche, B. & Reveillaud, J., May 2025, In: Microbiology Spectrum. 13, 5

Research output: Contribution to journalArticlepeer-review

Theory of host-microbe symbioses: Challenges and opportunities

Ferretti, P., Martignoni, M. M., McManus, L. C., Sakal, T., Liaghat, A., Stevens, B., Dahlin, K. J. M., Souza, L. S., Cardon, Z. G., Silveira, C. B., Bordenstein, S. R. & Roughgarden, J., Jul 9 2025, In: Cell Host and Microbe. 33, 7, p. 1052-1056 5 p.

Research output: Contribution to journalComment/debatepeer-review

Launching the IUCN Microbial Conservation Specialist Group as a global safeguard for microbial biodiversity

Gilbert, J. A., Peixoto, R. S., Scholz, A. H., Dominguez Bello, M. G., Korsten, L., Berg, G., Singh, B., Boetius, A., Wang, F., Greening, C., Wrighton, K., Bordenstein, S., Jansson, J. K., Lennon, J. T., Souza, V., Thomas, T., Cowan, D., Crowther, T. W., Nguyen, N. & Harper, L. & 3 others, Haraoui, L. P., Ishaq, S. L. & Redford, K., 2025, (Accepted/In press) In: Nature Microbiology.

Research output: Contribution to journalLetterpeer-review

Ecologically expanding the One Health framework to unify the microbiome sciences

Ginnan, N., Crandall, S. G., Imchen, M., Dini-Andreote, F., Miyashiro, T. I., Singh, V., Ganda, E. & Bordenstein, S. R., Jun 2025, In: mBio. 16, 6

Research output: Contribution to journalReview articlepeer-review

Cytoplasmic incompatibility factor proteins from Wolbachia prophage are costly to sperm development in Drosophila melanogaster

Kaur, R. & Bordenstein, S. R., Feb 12 2025, In: Proceedings of the Royal Society B: Biological Sciences. 292, 2040, 20243016.

Research output: Contribution to journalArticlepeer-review

Histone acetylation modulation by a small molecule inhibitor recapitulates symbiont-induced cytoplasmic incompatibility

Kaur, R., Kalra, M., Imchen, M., Crowley, B. L., McGarry, A., Carpenter, L. & Bordenstein, S. R., Oct 28 2025, In: Cell Reports. 44, 10, 116416.

Research output: Contribution to journalArticlepeer-review

Evolutionary Diversification and Functions of the Candidate Male Killing Gene wmk

Lefoulon, E., Bordenstein, S., Carpenter, L. R., Buchser, J. L., Nowicki, C. J., Yakhnina, A. A., Gutierrez, J. B., Kaur, R., Imchen, M. & Bordenstein, S. R., Oct 1 2025, In: Genome biology and evolution. 17, 10, evaf179.

Research output: Contribution to journalArticlepeer-review

Gut fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates

Van Syoc, E. P., Gomez, A., Davenport, E. R. & Bordenstein, S. R., Sep 1 2025, In: PLoS biology. 23, 9, p. e3003390

Research output: Contribution to journalArticlepeer-review

Gut fungi are associated with human genetic variation and disease risk

Van Syoc, E. P., Davenport, E. R. & Bordenstein, S. R., Sep 2025, In: PLoS biology. 23, 9 September, e3003339.

Research output: Contribution to journalArticlepeer-review

Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality

Kaur, R., McGarry, A., Dylan Shropshire, J., Leigh, B. A. & Bordenstein, S. R., Mar 8 2024, In: Science. 383, 6687, p. 1111-1117 7 p.

Research output: Contribution to journalArticlepeer-review

The mechanism of cytoplasmic incompatibility is conserved in Wolbachia-bearing Aedes aegypti mosquitoes deployed for arbovirus control

Kaur, R., Meier, C. J., McGraw, E. A., Hillyer, J. F. & Bordenstein, S. R., Mar 2024, In: PLoS biology. 22, 3, e3002573.

Research output: Contribution to journalArticlepeer-review

The disciplinary matrix of holobiont biology Uniting life’s seen and unseen realms guides a conceptual advance in research

The Holobiont Biology Network, Nov 15 2024, In: Science. 386, 6723, p. 731-732 2 p.

Research output: Contribution to journalArticlepeer-review

Low Gut Microbial Diversity Augments Estrogen-Driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease

Chioma, O. S., Mallott, E., Shah-Gandhi, B., Wiggins, Z. D., Langford, M., Lancaster, A. W., Gelbard, A., Wu, H., Johnson, J. E., Lancaster, L., Wilfong, E. M., Crofford, L. J., Montgomery, C. G., Van Kaer, L., Bordenstein, S., Newcomb, D. C. & Drake, W. P., Mar 2023, In: Cells. 12, 5, 766.

Research output: Contribution to journalArticlepeer-review

It is time to authenticate the Microbiome Sciences with accredited educational programs and departments

Ginnan, N. & Bordenstein, S. R., Dec 2023, In: PLoS biology. 21, 12, e3002420.

Research output: Contribution to journalArticlepeer-review

Human microbiome variation associated with race and ethnicity emerges as early as 3 months of age

Mallott, E. K., Sitarik, A. R., Leve, L. D., Cioffi, C., Camargo, C. A., Hasegawa, K. & Bordenstein, S. R., Aug 2023, In: PLoS biology. 21, 8 August, e3002230.

Research output: Contribution to journalArticlepeer-review