My research investigates how the human microbiome is influenced by environmental pressures, including pollution, food sources, water, etc. My team also investigates the history of environmental soil microbiomes and how anthropogenic forces have shaped them over time.
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Projects
Recent Publications
Guidelines for preventing and reporting contamination in low-biomass microbiome studies
Fierer, N., Leung, P. M., Lappan, R., Eisenhofer, R., Ricci, F., Holland, S. I., Dragone, N., Blackall, L. L., Dong, X., Dorador, C., Ferrari, B. C., Goordial, J., Holmes, S. P., Inagaki, F., Korem, T., Li, S. S., Makhalanyane, T. P., Metcalf, J. L., Nagarajan, N. & Orsi, W. D. & 10 others, , Jul 2025, In: Nature Microbiology. 10, 7, p. 1570-1580 11 p.Research output: Contribution to journal › Article › peer-review
The influence of diet, saliva, and dental history on the oral microbiome in healthy, caries-free Australian adults
Nath, S., Zilm, P., Jamieson, L., Santiago, P. H. R., Ketagoda, D. H. K. & Weyrich, L., Dec 2025, In: Scientific reports. 15, 1, 18755.Research output: Contribution to journal › Article › peer-review
SANA-Biome: A Protocol for a Cross-Sectional Study on Oral Health, Diet, and the Oral Microbiome in Romania
Wright, S. L., Slusanschi, O., Giura, A. C., Părlătescu, I., Funieru, C., Gaidula, S. M., Moore, N. & Weyrich, L. S., Sep 2025, In: Healthcare (Switzerland). 13, 17, 2133.Research output: Contribution to journal › Article › peer-review
Wet Lab Protocols Matter: Choice of DNA Extraction and Library Preparation Protocols Bias Ancient Oral Microbiome Recovery
Wright, S. L., Abdul-Aziz, M., Blaha, G. N., Ta, C. K., Gancz, A., Ademola-Popoola, I. J., Szécsényi-Nagy, A., Sereno, P. C. & Weyrich, L. S., Nov 2025, In: Molecular Ecology Resources. 25, 8, e70054.Research output: Contribution to journal › Article › peer-review
Off the beaten track: Understudied microbes and their potential
Adams, C., Gonçalves, A. P., Warring, S., Ettema, T. J. G., Weyrich, L. S. & Spriggs, C. C., Sep 19 2024, In: Cell. 187, 19, p. 5217-5219 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Assessing the Utility of Strontium Isotopes in Fossil Dental Calculus
Dosseto, A., Dux, F., Eisenhofer, R. & Weyrich, L., Sep 2024, In: Journal of Archaeological Method and Theory. 31, 3, p. 1570-1584 15 p.Research output: Contribution to journal › Article › peer-review
Benchmarking a targeted 16S ribosomal RNA gene enrichment approach to reconstruct ancient microbial communities
Eisenhofer, R., Wright, S. & Weyrich, L., 2024, In: PeerJ. 12, e16770.Research output: Contribution to journal › Article › peer-review
Ancient human dental calculus metadata collection and sampling strategies: Recommendations for best practices
Gancz, A. S., Wright, S. L. & Weyrich, L. S., Apr 2024, In: American Journal of Biological Anthropology. 183, 4, e24871.Research output: Contribution to journal › Article › peer-review
Development of an in vitro biofilm model of the human supra-gingival microbiome for Oral microbiome transplantation
Ketagoda, D. H. K., Varga, P., Fitzsimmons, T. R., Moore, N. E., Weyrich, L. S. & Zilm, P. S., Aug 2024, In: Journal of Microbiological Methods. 223, 106961.Research output: Contribution to journal › Article › peer-review
Characterising healthy Australian oral microbiomes for ‘super donor’ selection
Nath, S., Zilm, P., Jamieson, L., Ketagoda, D. H. K., Kapellas, K. & Weyrich, L., Dec 2024, In: Journal of Dentistry. 151, 105435.Research output: Contribution to journal › Article › peer-review
Oral microbiome research from a public health perspective and implications for oral health
Nath, S., Weyrich, L., Zilm, P., Kapellas, K. & Jamieson, L., Mar 1 2024, In: Community dental health. 41, 1, p. 75-82 8 p.Research output: Contribution to journal › Article › peer-review
Commercializing equitable, accessible oral microbiome transplantation therapy
Weyrich, L. S., Nath, S. & Jamieson, L., Mar 1 2024, In: Community dental health. 41, 1, p. 83-88 6 p.Research output: Contribution to journal › Article › peer-review
A relational framework for microbiome research with Indigenous communities
Bader, A. C., Van Zuylen, E. M., Handsley-Davis, M., Alegado, R. A., Benezra, A., Pollet, R. M., Ehau-Taumaunu, H., Weyrich, L. S. & Anderson, M. Z., Oct 2023, In: Nature Microbiology. 8, 10, p. 1768-1776 9 p.Research output: Contribution to journal › Article › peer-review
Ancient dental calculus reveals oral microbiome shifts associated with lifestyle and disease in Great Britain
Gancz, A. S., Farrer, A. G., Nixon, M. P., Wright, S., Arriola, L., Adler, C., Davenport, E. R., Gully, N., Cooper, A., Britton, K., Dobney, K., Silverman, J. D. & Weyrich, L. S., Dec 2023, In: Nature Microbiology. 8, 12, p. 2315-2325 11 p.Research output: Contribution to journal › Article › peer-review
Studying ancient human oral microbiomes could yield insights into the evolutionary history of noncommunicable diseases
Gancz, A. S. & Weyrich, L. S., 2023, In: F1000Research. 12, 109.Research output: Contribution to journal › Review article › peer-review