
Research Summary
Biological chemistry of RNA, characterization of RNA catalysis and folding, characterization of the RNA-dependent regulation of human viral response and RNA folding in plants as a response to environmental stress.
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Research Keywords
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Recent Publications
Regulatory Mechanisms through RNA Conformational Switching and Dynamics
Bevilacqua, P. C. & Tolbert, B. S., Sep 30 2022, In: Journal of Molecular Biology. 434, 18, 167794.Research output: Contribution to journal › Editorial › peer-review
RNA multimerization as an organizing force for liquid–liquid phase separation
Bevilacqua, P. C., Williams, A. M., Chou, H. L. & Assmann, S. M., Jan 2022, In: RNA. 28, 1, p. 16-26 11 p.Research output: Contribution to journal › Article › peer-review
Phase-specific RNA accumulation and duplex thermodynamics in multiphase coacervate models for membraneless organelles
Choi, S., Meyer, M. C. O., Bevilacqua, P. C. & Keating, C. D., 2022, (Accepted/In press) In: Nature Chemistry.Research output: Contribution to journal › Article › peer-review
Experimental demonstration and pan-structurome prediction of climate-associated riboSNitches in Arabidopsis
Ferrero-Serrano, Á., Sylvia, M. M., Forstmeier, P. C., Olson, A. J., Ware, D., Bevilacqua, P. C. & Assmann, S. M., Dec 2022, In: Genome biology. 23, 1, 101.Research output: Contribution to journal › Article › peer-review
Upstream Flanking Sequence Assists Folding of an RNA Thermometer
Jolley, E. A., Bormes, K. M. & Bevilacqua, P. C., Sep 30 2022, In: Journal of Molecular Biology. 434, 18, 167786.Research output: Contribution to journal › Article › peer-review
The Metabolome Weakens RNA Thermodynamic Stability and Strengthens RNA Chemical Stability
Sieg, J. P., McKinley, L. N., Huot, M. J., Yennawar, N. H. & Bevilacqua, P. C., Nov 15 2022, In: Biochemistry. 61, 22, p. 2579-2591 13 p.Research output: Contribution to journal › Article › peer-review
Biological solution conditions and flanking sequence modulate LLPS of RNA G-quadruplex structures
Williams, A. M., Dickson, T. M., Lagoa-Miguel, C. A. & Bevilacqua, P. C., Sep 1 2022, In: RNA (New York, N.Y.). 28, 9, p. 1197-1209 13 p.Research output: Contribution to journal › Article › peer-review
Genome-wide analysis of the in vivo tRNA structurome reveals RNA structural and modification dynamics under heat stress
Yamagami, R., Sieg, J. P., Assmann, S. M. & Bevilacqua, P. C., Jun 21 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 25, e2201237119.Research output: Contribution to journal › Article › peer-review
RNA sequence and structure control assembly and function of RNA condensates
Poudyal, R. R., Sieg, J. P., Portz, B., Keating, C. D. & Bevilacqua, P. C., Dec 1 2021, In: RNA (New York, N.Y.). 27, 12, p. 1589-1601 13 p.Research output: Contribution to journal › Article › peer-review
Investigation of the pKa of the nucleophilic O2' of the hairpin ribozyme
Veenis, A. J., Li, P., Soudackov, A. V., Hammes-Schiffer, S. & Bevilacqua, P. C., Nov 4 2021, In: Journal of Physical Chemistry B. 125, 43, p. 11869-11883 15 p.Research output: Contribution to journal › Article › peer-review
Long Tracts of Guanines Drive Aggregation of RNA G-Quadruplexes in the Presence of Spermine
Williams, A. M., Poudyal, R. R. & Bevilacqua, P. C., Sep 14 2021, In: Biochemistry. 60, 36, p. 2715-2726 12 p.Research output: Contribution to journal › Article › peer-review
Functional Roles of Chelated Magnesium Ions in RNA Folding and Function
Yamagami, R., Sieg, J. P. & Bevilacqua, P. C., Aug 10 2021, In: Biochemistry. 60, 31, p. 2374-2386 13 p.Research output: Contribution to journal › Review article › peer-review
Efficient construction of long DNA duplexes with internal non-Watson-Crick motifs and modifications
Zheng, X. & Bevilacqua, P. C., Jan 1 2021, In: Nucleic acids research. 29, 2, e6.Research output: Contribution to journal › Article › peer-review
Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments
Cakmak, F. P., Choi, S., Meyer, M. C. O., Bevilacqua, P. C. & Keating, C. D., Dec 2020, In: Nature communications. 11, 1, 5949.Research output: Contribution to journal › Article › peer-review
Csra-mediated translational activation of ymda expression in escherichia coli
Renda, A., Poly, S., Lai, Y. J., Pannuri, A., Yakhnin, H., Potts, A. H., Bevilacqua, P. C., Romeo, T. & Babitzke, P., Sep 1 2020, In: mBio. 11, 5, p. 1-12 12 p., e00849-20.Research output: Contribution to journal › Article › peer-review