Pamela Hankey

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IEE Research Themes
Affiliate Researcher
Titles and Affiliations
Professor, Veterinary and Biomedical Sciences

Research Summary

Role of receptor tyrosine kinases in normal physiology and disease progression and the downstream signals that mediate these responses in vitro and in vivo.

Research Keywords

Recent Publications

Metabolic profiling reveals aggravated non-alcoholic steatohepatitis in high-fat high-cholesterol diet-fed apolipoprotein e-deficient mice lacking ron receptor signaling

Allen, J. N., Dey, A., Cai, J., Zhang, J., Tian, Y., Kennett, M., Ma, Y., Liang, T. J., Patterson, A. D. & Hankey-Giblin, P. A., Aug 2020, In: Metabolites. 10, 8, p. 1-24 24 p., 326.

Research output: Contribution to journalArticlepeer-review

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Bennett, L. F., Liao, C., Quickel, M. D., Yeoh, B. S., Vijay-Kumar, M., Hankey-Giblin, P., Prabhu, K. S. & Paulson, R. F., Sep 10 2019, In: Science signaling. 12, 598, eaap7336.

Research output: Contribution to journalArticlepeer-review

Gab2 and Gab3 redundantly suppress colitis by modulating macrophage and CD8+ T-cell activation

Wang, Z., Vaughan, T. Y., Zhu, W., Chen, Y., Fu, G., Medrzycki, M., Nishio, H., Bunting, S. T., Hankey-Giblin, P. A., Nusrat, A., Parkos, C. A., Wang, D., Wen, R. & Bunting, K. D., 2019, In: Frontiers in immunology. 10, MAR, 486.

Research output: Contribution to journalArticlepeer-review

Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model

Allen, J., Zhang, J., Quickel, M. D., Kennett, M., Patterson, A. D. & Hankey-Giblin, P. A., Sep 7 2018, In: Journal of Proteome Research. 17, 9, p. 3268-3280 13 p.

Research output: Contribution to journalArticlepeer-review

Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder

Dey, A. & Giblin, P. A. H., Sep 2018, In: Pharmaceuticals. 11, 3, 64.

Research output: Contribution to journalReview articlepeer-review

Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease

Dey, A., Allen, J. N., Fraser, J. W., Snyder, L. M., Tian, Y., Zhang, L., Paulson, R. F., Patterson, A., Cantorna, M. T. & Hankey-Giblin, P. A., Mar 19 2018, In: Frontiers in immunology. 9, MAR, 513.

Research output: Contribution to journalArticlepeer-review

Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation

Allen, J. N., Dey, A., Nissly, R., Fraser, J., Yu, S., Balandaram, G., Peters, J. M. & Hankey-Giblin, P. A., Apr 3 2017, In: Journal of Visualized Experiments. 2017, 122, e55445.

Research output: Contribution to journalArticlepeer-review

Reduced competitive repopulation capacity of multipotential hematopoietic stem cells in the bone marrow of friend virus-infected Fv2-resistant mice

Epperly, M. W., Zhang, X., Fisher, R., Hou, W., Franicola, D., Shields, D., Quickel, M., Hankey-Giblin, P., Wang, H. & Greenberger, J. S., May 1 2017, In: In Vivo. 31, 3, p. 313-320 8 p.

Research output: Contribution to journalArticlepeer-review

Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria

Feaga, H. A., Quickel, M. D., Hankey-Giblin, P. A. & Keiler, K. C., Mar 2016, In: PLoS genetics. 12, 3, e1005964.

Research output: Contribution to journalArticlepeer-review

The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis

Yu, S., Allen, J. N., Dey, A., Zhang, L., Balandaram, G., Kennett, M. J., Xia, M., Xiong, N., Peters, J. M., Patterson, A. & Hankey-Giblin, P. A., Jul 1 2016, In: Journal of Immunology. 197, 1, p. 256-265 10 p.

Research output: Contribution to journalArticlepeer-review