Xiaojun "Lance" Lian

Affiliate Researcher
Titles and Affiliations
Associate Professor, Biomedical Engineering

In the News

Research Keywords

Recent Publications

A drug-selectable acoustic reporter gene system for human cell ultrasound imaging

Howells, A. R., Welch, P. J., Kim, J., Forest, C. R., Shi, C. & Lian, X. L., Mar 2024, In: Bioengineering and Translational Medicine. 9, 2, e10584.

Research output: Contribution to journalArticlepeer-review

CAR-neutrophil mediated delivery of tumor-microenvironment responsive nanodrugs for glioblastoma chemo-immunotherapy

Chang, Y., Cai, X., Syahirah, R., Yao, Y., Xu, Y., Jin, G., Bhute, V. J., Torregrosa-Allen, S., Elzey, B. D., Won, Y. Y., Deng, Q., Lian, X. L., Wang, X., Eniola-Adefeso, O. & Bao, X., Dec 2023, In: Nature communications. 14, 1, 2266.

Research output: Contribution to journalArticlepeer-review

Engineered Artificial Human Neutrophils Exhibit Mature Functional Performance

Chang, Y., Hummel, S. N., Watson, M. N., Jin, G., Lian, X. L. & Bao, X., Aug 18 2023, In: ACS Synthetic Biology. 12, 8, p. 2262-2270 9 p.

Research output: Contribution to journalArticlepeer-review

Engineered human pluripotent stem cell-derived natural killer cells with PD-L1 responsive immunological memory for enhanced immunotherapeutic efficacy

Chang, Y., Jin, G., Luo, W., Luo, Q., Jung, J., Hummel, S. N., Torregrosa-Allen, S., Elzey, B. D., Low, P. S., Lian, X. L. & Bao, X., Sep 2023, In: Bioactive Materials. 27, p. 168-180 13 p.

Research output: Contribution to journalArticlepeer-review

Chemically defined generation of human definitive hematopoietic stem and progenitor cells

Jung, J., Chang, Y., Jin, G., Deng, Q., Lian, X. L. & Bao, X., Mar 17 2023, In: STAR Protocols. 4, 1, 101953.

Research output: Contribution to journalArticlepeer-review

STAMP-Based Digital CRISPR-Cas13a for Amplification-Free Quantification of HIV-1 Plasma Viral Loads

Nouri, R., Jiang, Y., Politza, A. J., Liu, T., Greene, W. H., Zhu, Y., Nunez, J. J., Lian, X. & Guan, W., Jun 13 2023, In: ACS nano. 17, 11, p. 10701-10712 12 p.

Research output: Contribution to journalArticlepeer-review

Editorial: Bioengineered gene and cell therapy for treating cardiovascular diseases

Wang, K., Liu, X., Lian, X. L., Bao, X. & Li, K., 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1250175.

Research output: Contribution to journalEditorialpeer-review

Fabricating 3-dimensional human brown adipose microtissues for transplantation studies

Wang, O., Han, L., Lin, H., Tian, M., Zhang, S., Duan, B., Chung, S., Zhang, C., Lian, X., Wang, Y. & Lei, Y., Apr 2023, In: Bioactive Materials. 22, p. 518-534 17 p.

Research output: Contribution to journalArticlepeer-review

Chemically-defined generation of human hemogenic endothelium and definitive hematopoietic progenitor cells

Chang, Y., Syahirah, R., Oprescu, S. N., Wang, X., Jung, J., Cooper, S. H., Torregrosa-Allen, S., Elzey, B. D., Hsu, A. Y., Randolph, L. N., Sun, Y., Kuang, S., Broxmeyer, H. E., Deng, Q., Lian, X. & Bao, X., Jun 2022, In: Biomaterials. 285, 121569.

Research output: Contribution to journalArticlepeer-review

Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy

Chang, Y., Syahirah, R., Wang, X., Jin, G., Torregrosa-Allen, S., Elzey, B. D., Hummel, S. N., Wang, T., Li, C., Lian, X., Deng, Q., Broxmeyer, H. E. & Bao, X., Jul 19 2022, In: Cell Reports. 40, 3, 111128.

Research output: Contribution to journalArticlepeer-review

Robust genome editing via modRNA-based Cas9 or base editor in human pluripotent stem cells

Haideri, T., Howells, A., Jiang, Y., Yang, J., Bao, X. & Lian, X. L., Sep 19 2022, In: Cell Reports Methods. 2, 9, 100290.

Research output: Contribution to journalArticlepeer-review

Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems

Jiang, Y., Hoenisch, R. C., Chang, Y., Bao, X., Cameron, C. E. & Lian, X. L., Aug 2022, In: Bioactive Materials. 14, p. 313-320 8 p.

Research output: Contribution to journalArticlepeer-review

Temporal Expression of Transcription Factor ID2 Improves Natural Killer Cell Differentiation from Human Pluripotent Stem Cells

Jung, J., Chang, Y., Jin, G., Lian, X. & Bao, X., Jun 17 2022, In: ACS Synthetic Biology. 11, 6, p. 2001-2008 8 p.

Research output: Contribution to journalArticlepeer-review

Wnt signaling directs human pluripotent stem cells into vascularized cardiac organoids with chamber-like structures

Liang, P. Y., Chang, Y., Jin, G., Lian, X. & Bao, X., Nov 18 2022, In: Frontiers in Bioengineering and Biotechnology. 10, 1059243.

Research output: Contribution to journalArticlepeer-review

Erratum: Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction (Molecular Therapy (2018) 26(7) (1644–1659), (S1525001618300650), (10.1016/j.ymthe.2018.02.012))

Foo, K. S., Lehtinen, M. L., Leung, C. Y., Lian, X., Xu, J., Keung, W., Geng, L., Kolstad, T. R. S., Thams, S., Wong, A. O. T., Wong, N., Bylund, K., Zhou, C., He, X., Jin, S. B., Clarke, J., Lendahl, U., Li, R. A., Louch, W. E. & Chien, K. R., Jan 6 2021, In: Molecular Therapy. 29, 1, p. 409 1 p.

Research output: Contribution to journalComment/debatepeer-review