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Recent Publications
Lignin impairs Cel7A degradation of in vitro lignified cellulose by impeding enzyme movement and not by acting as a sink
Haviland, Z. K., Nong, D., Zexer, N., Tien, M., Anderson, C. T. & Hancock, W. O., Dec 2024, In: Biotechnology for Biofuels and Bioproducts. 17, 1, 7.Research output: Contribution to journal › Article › peer-review
Simulations suggest robust microtubule attachment of kinesin and dynein in antagonistic pairs
Ma, T. C., Gicking, A. M., Feng, Q. & Hancock, W. O., Aug 22 2023, In: Biophysical journal. 122, 16, p. 3299-3313 15 p.Research output: Contribution to journal › Article › peer-review
KIF1A is kinetically tuned to be a superengaging motor under hindering loads
Pyrpassopoulos, S., Gicking, A. M., Zaniewski, T. M., Hancock, W. O. & Ostap, E. M., Jan 10 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 2, e2216903120.Research output: Contribution to journal › Article › peer-review
Positive charge in the K-loop of the kinesin-3 motor KIF1A regulates superprocessivity by enhancing microtubule affinity in the one-head–bound state
Zaniewski, T. M. & Hancock, W. O., Feb 2023, In: Journal of Biological Chemistry. 299, 2, 102818.Research output: Contribution to journal › Article › peer-review
Measurements and simulations of microtubule growth imply strong longitudinal interactions and reveal a role for GDP on the elongating end
Cleary, J. M., Kim, T., Cook, A. S. I., McCormick, L. A., Hancock, W. O. & Rice, L. M., Apr 2022, In: eLife. 11, e75931.Research output: Contribution to journal › Article › peer-review
Kinesin-1,-2, and-3 motors use family-specific mechanochemical strategies to effectively compete with dynein during bidirectional transport
Gicking, A. M., Ma, T. C., Feng, Q., Jiang, R., Badieyan, S., Cianfrocco, M. A. & Hancock, W. O., Sep 2022, In: eLife. 11, e82228.Research output: Contribution to journal › Article › peer-review
Intracellular transport: KIF1C produces force along with a few slips
Hancock, W. O., Sep 12 2022, In: Current Biology. 32, 17, p. R914-R916Research output: Contribution to journal › Comment/debate › peer-review
Synergy between inhibitors of two mitotic spindle assembly motors undermines an adaptive response
Solon, A. L., Zaniewski, T. M., O’Brien, P., Clasby, M., Hancock, W. O. & Ohi, R., Dec 1 2022, In: Molecular biology of the cell. 33, 14, ar132.Research output: Contribution to journal › Article › peer-review
Measurement of the persistence length of cytoskeletal filaments using curvature distributions
Wisanpitayakorn, P., Mickolajczyk, K. J., Hancock, W. O., Vidali, L. & Tüzel, E., May 17 2022, In: Biophysical journal. 121, 10, p. 1813-1822 10 p.Research output: Contribution to journal › Article › peer-review
Molecular mechanisms underlying microtubule growth dynamics
Cleary, J. M. & Hancock, W. O., May 24 2021, In: Current Biology. 31, 10, p. R560-R573Research output: Contribution to journal › Review article › peer-review
Trim9 and Klp61F promote polymerization of new dendritic microtubules along parallel microtubules
Feng, C., Cleary, J. M., Kothe, G. O., Stone, M. C., Weiner, A. T., Hertzler, J. I., Hancock, W. O. & Rolls, M. M., Jun 2021, In: Journal of Cell Science. 134, 11, jcs258437.Research output: Contribution to journal › Article › peer-review
Nanoscale dynamics of cellulose digestion by the cellobiohydrolase TrCel7A
Haviland, Z. K., Nong, D., Kuntz, K. L. V., Starr, T. J., Ma, D., Tien, M., Anderson, C. T. & Hancock, W. O., Sep 1 2021, In: Journal of Biological Chemistry. 297, 3, 101029.Research output: Contribution to journal › Article › peer-review
A change point analysis protocol for comparing intracellular transport by different molecular motor combinations
Jensen, M. A., Feng, Q., Hancock, W. O. & McKinley, S. A., 2021, In: Mathematical Biosciences and Engineering. 18, 6, p. 8962-8996 35 p.Research output: Contribution to journal › Article › peer-review
Measuring microtubule binding kinetics of membrane-bound kinesin motors using supported lipid bilayers
Jiang, R. & Hancock, W. O., Sep 17 2021, In: STAR Protocols. 2, 3, 100691.Research output: Contribution to journal › Article › peer-review
Integrated multi-wavelength microscope combining TIRFM and IRM modalities for imaging cellulases and other processive enzymes
Nong, D., Haviland, Z. K., Kuntz, K. V., Tien, M., Anderson, C. T. & Hancock, W. O., Jun 1 2021, In: Biomedical Optics Express. 12, 6, p. 3253-3264 12 p.Research output: Contribution to journal › Review article › peer-review