William Hancock

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Professor, Biomedical Engineering

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Recent Publications

Molecular mechanisms underlying microtubule growth dynamics

Cleary, J. M. & Hancock, W. O., May 24 2021, In: Current Biology. 31, 10, p. R560-R573

Research output: Contribution to journalReview articlepeer-review

Trim9 and Klp61F promote polymerization of new dendritic microtubules along parallel microtubules

Feng, C., Cleary, J. M., Kothe, G. O., Stone, M. C., Weiner, A. T., Hertzler, J. I., Hancock, W. O. & Rolls, M. M., Jun 2021, In: Journal of Cell Science. 134, 11, jcs258437.

Research output: Contribution to journalArticlepeer-review

Nanoscale dynamics of cellulose digestion by the cellobiohydrolase TrCel7A

Haviland, Z. K., Nong, D., Kuntz, K. L. V., Starr, T. J., Ma, D., Tien, M., Anderson, C. T. & Hancock, W. O., Sep 1 2021, In: Journal of Biological Chemistry. 297, 3, 101029.

Research output: Contribution to journalArticlepeer-review

A change point analysis protocol for comparing intracellular transport by different molecular motor combinations

Jensen, M. A., Feng, Q., Hancock, W. O. & McKinley, S. A., 2021, In: Mathematical Biosciences and Engineering. 18, 6, p. 8962-8996 35 p.

Research output: Contribution to journalArticlepeer-review

Measuring microtubule binding kinetics of membrane-bound kinesin motors using supported lipid bilayers

Jiang, R. & Hancock, W. O., Sep 17 2021, In: STAR Protocols. 2, 3, 100691.

Research output: Contribution to journalArticlepeer-review

Integrated multi-wavelength microscope combining TIRFM and IRM modalities for imaging cellulases and other processive enzymes

Nong, D., Haviland, Z. K., Kuntz, K. V., Tien, M., Anderson, C. T. & Hancock, W. O., Jun 1 2021, In: Biomedical Optics Express. 12, 6, p. 3253-3264 12 p.

Research output: Contribution to journalReview articlepeer-review

Dynactin p150 promotes processive motility of DDB complexes by minimizing diffusional behavior of dynein

Feng, Q., Gicking, A. M. & Hancock, W. O., Mar 2020, In: Molecular biology of the cell. 31, 8, p. 782-792 11 p.

Research output: Contribution to journalArticlepeer-review

What is the correct stoichiometry of Kv2.1:Kv6.4 heteromers?

Pisupati, A., Mickolajczyk, K. J., Hancock, W. O. & Jegla, T., Nov 24 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 47, p. 29288-29289 2 p.

Research output: Contribution to journalLetterpeer-review

Kinesin-2 from C. reinhardtii Is an Atypically Fast and Auto-inhibited Motor that Is Activated by Heterotrimerization for Intraflagellar Transport

Sonar, P., Youyen, W., Cleetus, A., Wisanpitayakorn, P., Mousavi, S. I., Stepp, W. L., Hancock, W. O., Tüzel, E. & Ökten, Z., Mar 23 2020, In: Current Biology. 30, 6, p. 1160-1166.e5

Research output: Contribution to journalArticlepeer-review

The Tail of Kinesin-14a in Giardia Is a Dual Regulator of Motility

Tseng, K. F., Mickolajczyk, K. J., Feng, G., Feng, Q., Kwok, E. S., Howe, J., Barbar, E. J., Dawson, S. C., Hancock, W. O. & Qiu, W., Sep 21 2020, In: Current Biology. 30, 18, p. 3664-3671.e4

Research output: Contribution to journalArticlepeer-review