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Recent Publications
Seeing Is Believing: Advances in Biological Imaging
Zhang, X. & Booker, S. J., Feb 21 2024, In: ACS Bio and Med Chem Au. 4, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › peer-review
FDX1 regulates cellular protein lipoylation through direct binding to LIAS
Dreishpoon, M. B., Bick, N. R., Petrova, B., Warui, D. M., Cameron, A., Booker, S. J., Kanarek, N., Golub, T. R. & Tsvetkov, P., Sep 2023, In: Journal of Biological Chemistry. 299, 9, 105046.Research output: Contribution to journal › Article › peer-review
How synonymous mutations alter enzyme structure and function over long timescales
Jiang, Y., Neti, S. S., Sitarik, I., Pradhan, P., To, P., Xia, Y., Fried, S. D., Booker, S. J. & O’Brien, E. P., Mar 2023, In: Nature Chemistry. 15, 3, p. 308-318 11 p.Research output: Contribution to journal › Article › peer-review
Enzymatic Fluoromethylation Enabled by the S-Adenosylmethionine Analog Te-Adenosyl- L-(fluoromethyl)homotellurocysteine
Neti, S. S., Wang, B., Iwig, D. F., Onderko, E. L. & Booker, S. J., May 24 2023, In: ACS Central Science. 9, 5, p. 905-914 10 p.Research output: Contribution to journal › Article › peer-review
Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2
Schulz, V., Basu, S., Freibert, S. A., Webert, H., Boss, L., Mühlenhoff, U., Pierrel, F., Essen, L. O., Warui, D. M., Booker, S. J., Stehling, O. & Lill, R., Feb 2023, In: Nature Chemical Biology. 19, 2, p. 206-217 12 p.Research output: Contribution to journal › Article › peer-review
Happy Birthday ACS Bio & Med Chem Au!
Booker, S. J., Feb 16 2022, In: ACS Bio and Med Chem Au. 2, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › peer-review
Twenty Years of Radical SAM! the Genesis of the Superfamily
Booker, S. J. & Lloyd, C. T., Dec 21 2022, In: ACS Bio and Med Chem Au. 2, 6, p. 538-547 10 p.Research output: Contribution to journal › Review article › peer-review
Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis
Knox, H. L., Sinner, E. K., Townsend, C. A., Boal, A. K. & Booker, S. J., Feb 10 2022, In: Nature. 602, 7896, p. 343-348 6 p.Research output: Contribution to journal › Article › peer-review
Discovery, structure and mechanism of a tetraether lipid synthase
Lloyd, C. T., Iwig, D. F., Wang, B., Cossu, M., Metcalf, W. W., Boal, A. K. & Booker, S. J., Sep 1 2022, In: Nature. 609, 7925, p. 197-203 7 p.Research output: Contribution to journal › Article › peer-review
Characterization of LipS1 and LipS2 from Thermococcus kodakarensis: Proteins Annotated as Biotin Synthases, which Together Catalyze Formation of the Lipoyl Cofactor
Neti, S. S., Sil, D., Warui, D. M., Esakova, O. A., Solinski, A. E., Serrano, D. A., Krebs, C. & Booker, S. J., Oct 19 2022, In: ACS Bio and Med Chem Au. 2, 5, p. 509-520 12 p.Research output: Contribution to journal › Article › peer-review
[FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis
Pagnier, A., Balci, B., Shepard, E. M., Yang, H., Warui, D. M., Impano, S., Booker, S. J., Hoffman, B. M., Broderick, W. E. & Broderick, J. B., May 23 2022, In: Angewandte Chemie - International Edition. 61, 22, e202203413.Research output: Contribution to journal › Article › peer-review
In Vitro Demonstration of Human Lipoyl Synthase Catalytic Activity in the Presence of NFU1
Warui, D. M., Sil, D., Lee, K. H., Neti, S. S., Esakova, O. A., Knox, H. L., Krebs, C. & Booker, S. J., Oct 19 2022, In: ACS Bio and Med Chem Au. 2, 5, p. 456-468 13 p.Research output: Contribution to journal › Article › peer-review
Welcome to ACS Bio & Med Chem Au
Booker, S. J., Conway, S. J. & Lavasanifar, A., Dec 15 2021, In: ACS Bio and Med Chem Au. 1, 1, p. 1 1 p.Research output: Contribution to journal › Editorial › peer-review
Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB
Esakova, O. A., Grove, T. L., Yennawar, N. H., Arcinas, A. J., Wang, B., Krebs, C., Almo, S. C. & Booker, S. J., Sep 23 2021, In: Nature. 597, 7877, p. 566-570 5 p.Research output: Contribution to journal › Article › peer-review
Structural basis for non-radical catalysis by TsrM, a radical SAM methylase
Knox, H. L., Chen, P. Y. T., Blaszczyk, A. J., Mukherjee, A., Grove, T. L., Schwalm, E. L., Wang, B., Drennan, C. L. & Booker, S. J., Apr 2021, In: Nature Chemical Biology. 17, 4, p. 485-491 7 p.Research output: Contribution to journal › Article › peer-review