Seth Bordenstein

Affiliate Researcher
Titles and Affiliations
Professor, Biology
Professor, Entomology
Dorothy Foehr Huck and J. Lloyd Huck Endowed Chair in Microbiome Sciences and Director of the Microbiome Center, Huck Institutes of the Life Sciences

In the News

Research Keywords

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Recent Publications

Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality

Kaur, R., McGarry, A., Dylan Shropshire, J., Leigh, B. A. & Bordenstein, S. R., Mar 8 2024, In: Science. 383, 6687, p. 1111-1117 7 p.

Research output: Contribution to journalArticlepeer-review

The mechanism of cytoplasmic incompatibility is conserved in Wolbachia-bearing Aedes aegypti mosquitoes deployed for arbovirus control

Kaur, R., Meier, C. J., McGraw, E. A., Hillyer, J. F. & Bordenstein, S. R., Mar 2024, In: PLoS biology. 22, 3, e3002573.

Research output: Contribution to journalArticlepeer-review

Low Gut Microbial Diversity Augments Estrogen-Driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease

Chioma, O. S., Mallott, E., Shah-Gandhi, B., Wiggins, Z. D., Langford, M., Lancaster, A. W., Gelbard, A., Wu, H., Johnson, J. E., Lancaster, L., Wilfong, E. M., Crofford, L. J., Montgomery, C. G., Van Kaer, L., Bordenstein, S., Newcomb, D. C. & Drake, W. P., Mar 2023, In: Cells. 12, 5, 766.

Research output: Contribution to journalArticlepeer-review

It is time to authenticate the Microbiome Sciences with accredited educational programs and departments

Ginnan, N. & Bordenstein, S. R., Dec 2023, In: PLoS biology. 21, 12, e3002420.

Research output: Contribution to journalArticlepeer-review

Human microbiome variation associated with race and ethnicity emerges as early as 3 months of age

Mallott, E. K., Sitarik, A. R., Leve, L. D., Cioffi, C., Camargo, C. A., Hasegawa, K. & Bordenstein, S. R., Aug 2023, In: PLoS biology. 21, 8 August, e3002230.

Research output: Contribution to journalArticlepeer-review

A Margulian View of Symbiosis and Speciation: the Nasonia Wasp System

Bell, K. & Bordenstein, S. R., May 2022, In: Symbiosis. 87, 1, p. 3-10 8 p.

Research output: Contribution to journalArticlepeer-review

Widespread phages of endosymbionts: Phage WO genomics and the proposed taxonomic classification of Symbioviridae

Bordenstein, S. R. & Bordenstein, S. R., Jun 6 2022, In: PLoS genetics. 18, 6, e1010227.

Research output: Contribution to journalArticlepeer-review

Gut microbiota modulates lung fibrosis severity following acute lung injury in mice

Chioma, O. S., Mallott, E. K., Chapman, A., Van Amburg, J. C., Wu, H., Shah-Gandhi, B., Dey, N., Kirkland, M. E., Blanca Piazuelo, M., Johnson, J., Bernard, G. R., Bodduluri, S. R., Davison, S., Haribabu, B., Bordenstein, S. R. & Drake, W. P., Dec 2022, In: Communications Biology. 5, 1, 1401.

Research output: Contribution to journalArticlepeer-review

The Cif proteins from Wolbachia prophage WO modify sperm genome integrity to establish cytoplasmic incompatibility

Kaur, R., Leigh, B. A., Ritchie, I. T. & Bordenstein, S. R., May 2022, In: PLoS biology. 20, 5, e3001584.

Research output: Contribution to journalArticlepeer-review

Individuality and ethnicity eclipse a short-term dietary intervention in shaping microbiomes and viromes

Li, J., Markowitz, R. H. G., Brooks, A. W., Mallott, E. K., Leigh, B. A., Olszewski, T., Zare, H., Bagheri, M., Smith, H. M., Friese, K. A., Habibi, I., Lawrence, W. M., Rost, C. L., Lédeczi, Á., Eeds, A. M., Ferguson, J. F., Silver, H. J. & Bordenstein, S. R., Aug 2022, In: PLoS biology. 20, 8, e3001758.

Research output: Contribution to journalArticlepeer-review

Microbiome-associated human genetic variants impact phenome-wide disease risk

Markowitz, R. H. G., LaBella, A. L., Shi, M., Rokas, A., Capra, J. A., Ferguson, J. F., Mosley, J. D. & Bordenstein, S. R., Jun 28 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 26, e2200551119.

Research output: Contribution to journalArticlepeer-review

Transgenic cytoplasmic incompatibility persists across age and temperature variation in Drosophila melanogaster

Ritchie, I. T., Needles, K. T., Leigh, B. A., Kaur, R. & Bordenstein, S. R., Nov 18 2022, In: iScience. 25, 11, 105327.

Research output: Contribution to journalArticlepeer-review

Microbiome reduction and endosymbiont gain from a switch in sea urchin life history

Carrier, T. J., Leigh, B. A., Deaker, D. J., Devens, H. R., Wray, G. A., Bordenstein, S. R., Byrne, M. & Reitzel, A. M., Apr 20 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 16, e2022023118.

Research output: Contribution to journalArticlepeer-review

Genomes of gut bacteria from nasonia wasps shed light on phylosymbiosis and microbe-assisted hybrid breakdown

Cross, K. L., Leigh, B. A., Hatmaker, E. A., Mikaelyan, A., Miller, A. K. & Bordenstein, S. R., Apr 2021, In: mSystems. 6, 2, e01342-20.

Research output: Contribution to journalArticlepeer-review

The impact of artificial selection for wolbachia-mediated dengue virus blocking on phage wo

Dutra, H. L. C., Ford, S. A., Allen, S. L., Bordenstein, S. R., Chenoweth, S. F., Bordenstein, S. R. & McGraw, E. A., Jul 2021, In: PLoS neglected tropical diseases. 15, 7, e0009637.

Research output: Contribution to journalArticlepeer-review