Sergei Koshkin

Affiliate Researcher
Titles and Affiliations
Assistant Research Professor, Huck Institutes of the Life Sciences

In the News

Research Keywords

Recent Publications

Bezafibrate improves mitochondrial function, blood-brain barrier integrity, and social deficits in models of 22q11.2 deletion syndrome

Crockett, A. M., Vélez Colόn, M. C., Kebir, H., Smith, F. M., Iascone, D. M., Ciesielski, B., Koshkin, S., Patterson, A. D., Rossano, A. J., Sehgal, A., Anderson, S. A. & Alvarez, J. I., Aug 20 2025, In: Science Translational Medicine. 17, 812, eads2116.

Research output: Contribution to journalArticlepeer-review

Effect of Varying Quantities of Lean Beef as Part of a Mediterranean-Style Dietary Pattern on Gut Microbiota and Plasma, Fecal, and Urinary Metabolites: A Randomized Crossover Controlled Feeding Trial

DiMattia, Z. S., Zhao, J., Hao, F., Koshkin, S., Bisanz, J. E., Patterson, A. D., Fleming, J. A., Kris-Etherton, P. M. & Petersen, K., Oct 7 2025, In: Journal of the American Heart Association. 14, 19, p. e041063

Research output: Contribution to journalArticlepeer-review

Evaluation of Antiseptic Drug Candidate Pyridosept in Preclinical in Vitro Studies

Kazakova, R., Iksanova, A., Agafonova, M., Lubina, A., Bulatova, E., Nikitina, E., Lisovskaya, S., Kayumov, A., Bondar, O., Malanyeva, A., Vasileva, O., Zeldi, M., Gatina, A., Koshkin, S., Komcharova, N., Konyakhina, Y., Titova, K., Sergeev, A., Sapozhnikov, S. & Shtyrlin, N. & 1 others, Shtyrlin, Y., 2025, In: Current Medicinal Chemistry. 32, 36, p. 8171-8181 11 p.

Research output: Contribution to journalArticlepeer-review

Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice

Tian, Y., Rimal, B., Bisanz, J. E., Gui, W., Wolfe, T. M., Koo, I., Murray, I. A., Nettleford, S. K., Yokoyama, S., Dong, F., Koshkin, S., Prabhu, K. S., Turnbaugh, P. J., Walk, S. T., Perdew, G. H. & Patterson, A. D., Aug 2024, In: Environmental health perspectives. 132, 8, 087005.

Research output: Contribution to journalArticlepeer-review

Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose

Tung, H. C., Kim, J. W., Zhu, J., Li, S., Yan, J., Liu, Q., Koo, I., Koshkin, S. A., Hao, F., Zhong, G., Xu, M., Wang, Z., Wang, J., Huang, Y., Xi, Y., Cai, X., Xu, P., Ren, S., Higashiyama, T. & Gonzalez, F. J. & 6 others, Li, S., Isoherranen, N., Yang, D., Ma, X., Patterson, A. D. & Xie, W., Sep 25 2024, In: Science Translational Medicine. 16, 766, eadk8446.

Research output: Contribution to journalArticlepeer-review

Prebiotic Syntheses Under Shock in the Water – Formamide – Potassium Bicarbonate – Sodium Hydroxide System

Shtyrlin, V. G., Borissenok, V. A., Serov, N. Y., Simakov, V. G., Bragunets, V. A., Trunin, I. R., Tereshkina, I. A., Koshkin, S. A., Bukharov, M. S., Gilyazetdinov, E. M., Shestakov, E. E., Sirotkina, A. G. & Zakharov, A. V., Jun 15 2019, In: Origins of Life and Evolution of Biospheres. 49, 1-2, p. 1-18 18 p.

Research output: Contribution to journalArticlepeer-review

C-547, a 6-methyluracil derivative with long-lasting binding and rebinding on acetylcholinesterase: Pharmacokinetic and pharmacodynamic studies

Petrov, K., Zueva, I., Kovyazina, I., Sedov, I., Lushchekina, S., Kharlamova, A., Lenina, O., Koshkin, S., Shtyrlin, Y., Nikolsky, E. & Masson, P., Mar 15 2018, In: Neuropharmacology. 131, p. 304-315 12 p.

Research output: Contribution to journalArticlepeer-review

Synthesis of a new quaternary phosphonium salt: NMR study of the conformational structure and dynamics

Aganova, O. V., Galiullina, L. F., Aganov, A. V., Shtyrlin, N. V., Pugachev, M. V., Strel'nik, A. D., Koshkin, S. A., Shtyrlin, Y. G. & Klochkov, V. V., Apr 1 2016, In: Magnetic Resonance in Chemistry. 54, 4, p. 320-327 8 p.

Research output: Contribution to journalArticlepeer-review

Synthesis of lipophilic N-phosphorylmethylated amino acids and their membrane-transport properties towards some organic acids

Cherkasov, R. A., Koshkin, S. A., Garifzyanov, A. R. & Davletshina, N. V., Dec 1 2016, In: Phosphorus, Sulfur and Silicon and the Related Elements. 191, 11-12, p. 1650-1651 2 p.

Research output: Contribution to journalArticlepeer-review

Synthesis of silyl esters of phosphorylated derivatives of sarcosine

Davletshin, R. R., Davletshina, N. V., Koshkin, S. A., Garifzyanov, A. R. & Cherkasov, R. A., Nov 1 2016, In: Russian Journal of General Chemistry. 86, 11, p. 2562-2563 2 p.

Research output: Contribution to journalLetterpeer-review

Synthesis and antiadrenergic properties of β-substituted alcohols based on 6-hydroxymethylpyridoxine

Pavelyev, R. S., Khairullina, R. R., Koshkin, S. A., Iksanova, A. G., Lodochnikova, O. A., Khaertdinov, N. N., Sitdikova, G. F., Safina, A. F., Aleksandrova, E. G., Ziganshina, L. E. & Shtyrlin, Y. G., Feb 1 2016, In: Russian Chemical Bulletin. 65, 2, p. 519-531 13 p.

Research output: Contribution to journalArticlepeer-review

Membrane transport of alkali metals with phosphorylmethyl derivatives of amino acids

Davletshina, N. V., Koshkin, S. A., Garifzyanov, A. R., Davletshin, R. R., Filimonova, M. A. & Cherkasov, R. A., Jul 17 2015, In: Russian Journal of General Chemistry. 85, 7, p. 1791-1792 2 p.

Research output: Contribution to journalArticlepeer-review

Synthesis and membrane-transport properties of new lithium-selective extracting agent, tris(O,O-diamylphosphorylmethyl)amine

Davletshina, N. V., Koshkin, S. A., Garifzyanov, A. R., Filimonova, M. A., Gainullin, A. Z. & Cherkasov, R. A., Sep 1 2015, In: Russian Journal of General Chemistry. 85, 9, p. 2198-2199 2 p.

Research output: Contribution to journalArticlepeer-review

Reaction of 3-methylbuta-1,2-dien-1-ylphosphonates with benzimidazole and 2-aminobenzimidazole

Khusainova, N. G., Samigullin, D. I. & Koshkin, S. A., Sep 1 2015, In: Russian Journal of Organic Chemistry. 51, 9, p. 1353-1355 3 p.

Research output: Contribution to journalArticlepeer-review

Liquid extraction of metal ions with phosphonate derivatives of amino acids

Koshkin, S. A., Garifzyanov, A. R., Davletshina, N. V., Davletshin, R. R., Chibirev, E. O. & Cherkasov, R. A., Jul 17 2015, In: Russian Journal of General Chemistry. 85, 7, p. 1789-1790 2 p.

Research output: Contribution to journalArticlepeer-review