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Recent Publications
From molecular descriptions to cellular functions of intrinsically disordered protein regions
Chen, W., Fraser, O. A., George, C. & Showalter, S. A., Dec 1 2024, In: Biophysics Reviews. 5, 4, 041306.Research output: Contribution to journal › Review article › peer-review
Acetylation-Dependent Compaction of the Histone H4 Tail Ensemble
Dewing, S. M., Phan, T. M., Kraft, E. J., Mittal, J. & Showalter, S. A., Oct 31 2024, In: Journal of Physical Chemistry B. 128, 43, p. 10636-10649 14 p.Research output: Contribution to journal › Article › peer-review
Molecular insights into the interaction between a disordered protein and a folded RNA
Mitra, R., Usher, E. T., Dedeoǧlu, S., Crotteau, M. J., Fraser, O. A., Yennawar, N. H., Gadkari, V. V., Ruotolo, B. T., Holehouse, A. S., Salmon, L., Showalter, S. A. & Bardwell, J. C. A., Dec 3 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 49, e2409139121.Research output: Contribution to journal › Article › peer-review
A direct nuclear magnetic resonance method to investigate lysine acetylation of intrinsically disordered proteins
Fraser, O. A., Dewing, S. M., Usher, E. T., George, C. & Showalter, S. A., Jan 6 2023, In: Frontiers in Molecular Biosciences. 9, 1074743.Research output: Contribution to journal › Article › peer-review
Advances in direct detection of lysine methylation and acetylation by nuclear magnetic resonance using 13C-enriched cofactors
Fraser, O. A., Namitz, K. E. W. & Showalter, S. A., Oct 2023, In: Methods. 218, p. 72-83 12 p.Research output: Contribution to journal › Article › peer-review
Phase separation promotes a highly active oligomeric scaffold of the MLL1 core complex for regulation of histone H3K4 methylation
Namitz, K. E. W., Showalter, S. A. & Cosgrove, M. S., Oct 2023, In: Journal of Biological Chemistry. 299, 10, 105204.Research output: Contribution to journal › Article › peer-review
Biophysical insights into glucose-dependent transcriptional regulation by PDX1
Usher, E. T. & Showalter, S. A., Dec 2022, In: Journal of Biological Chemistry. 298, 12, 102623.Research output: Contribution to journal › Review article › peer-review
Transient Electrostatic Interactions between Fcp1 and Rap74 Bias the Conformational Ensemble of the Complex with Minimal Impact on Binding Affinity
Prieto, V. A., Namitz, K. E. W. & Showalter, S. A., Oct 7 2021, In: Journal of Physical Chemistry B. 125, 39, p. 10917-10927 11 p.Research output: Contribution to journal › Article › peer-review
Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity
Usher, E. T., Sabri, N., Rohac, R., Boal, A. K., Mittag, T. & Showalter, S. A., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100693.Research output: Contribution to journal › Article › peer-review
Probing multiple enzymatic methylation events in real time with NMR spectroscopy
Usher, E. T., Namitz, K. E. W., Cosgrove, M. S. & Showalter, S. A., Nov 2 2021, In: Biophysical journal. 120, 21, p. 4710-4721 12 p.Research output: Contribution to journal › Article › peer-review
An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
Morley, V. J., Kinnear, C. L., Sim, D. G., Olson, S. N., Jackson, L. M., Hansen, E., Usher, G. A., Showalter, S. A., Pai, M. P., Woods, R. J. & Read, A. F., Dec 1 2020, In: eLife. 9, p. 1-17 17 p., e58147.Research output: Contribution to journal › Article › peer-review
Elucidating the Role of Microprocessor Protein DGCR8 in Bending RNA Structures
Pabit, S. A., Chen, Y. L., Usher, E. T., Cook, E. C., Pollack, L. & Showalter, S. A., Dec 15 2020, In: Biophysical journal. 119, 12, p. 2524-2536 13 p.Research output: Contribution to journal › Article › peer-review
Reviving Protein-Observed 19F Lineshape Analysis for Deep Insight into Protein-Ligand Binding Events
Showalter, S. A., May 19 2020, In: Biophysical journal. 118, 10, p. 2333-2335 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks
Sloand, J. N., Nguyen, T. T., Zinck, S. A., Cook, E. C., Zimudzi, T. J., Showalter, S. A., Glick, A. B., Simon, J. C. & Medina, S. H., Apr 28 2020, In: ACS nano. 14, 4, p. 4061-4073 13 p.Research output: Contribution to journal › Article › peer-review
Mapping invisible epitopes by NMR spectroscopy
Usher, E. T. & Showalter, S. A., Dec 18 2020, In: Journal of Biological Chemistry. 295, 51, p. 17411-17412 2 p.Research output: Contribution to journal › Review article › peer-review