Jeffrey Peters

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IEE Research Themes
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Titles and Affiliations
Distinguished Professor, Veterinary and Biomedical Sciences
Deputy Director, Penn State Cancer Institute

Research Summary

Studies the role of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology and carcinogenesis, with a particular interest in epithelial and liver cancer. He aims to identify new molecules/proteins that can be targeted with existing approaches to improve the efficacy of chemoprevention and chemotherapy. His studies may allow for the development of dietary formulations of agricultural products that will improve human and animal health and prevent serious diseases.

In the News

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Recent Publications

Current Challenges and Recent Developments in Mass Spectrometry-Based Metabolomics

Collins, S. L., Koo, I., Peters, J. M., Smith, P. B. & Patterson, A. D., 2021, In: Annual Review of Analytical Chemistry. 14, p. 467-487 21 p.

Research output: Contribution to journalReview articlepeer-review

Diminished Hepatocarcinogenesis by a Potent, High-Affinity Human PPARα Agonist in PPARA-Humanized Mice

Foreman, J. E., Koga, T., Kosyk, O., Kang, B. H., Zhu, X., Cohen, S. M., Billy, L. J., Sharma, A. K., Amin, S., Gonzalez, F. J., Rusyn, I. & Peters, J. M., Sep 1 2021, In: Toxicological Sciences. 183, 1, p. 70-80 11 p.

Research output: Contribution to journalArticlepeer-review

Species Differences between Mouse and Human PPARα in Modulating the Hepatocarcinogenic Effects of Perinatal Exposure to a High-Affinity Human PPARα Agonist in Mice

Foreman, J. E., Koga, T., Kosyk, O., Kang, B. H., Zhu, X., Cohen, S. M., Billy, L. J., Sharma, A. K., Amin, S., Gonzalez, F. J., Rusyn, I. & Peters, J. M., Sep 1 2021, In: Toxicological Sciences. 183, 1, p. 81-92 12 p.

Research output: Contribution to journalArticlepeer-review

Change is Good: What is New for ToxSci?

Peters, J. M., Jan 1 2020, In: Toxicological Sciences. 173, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorialpeer-review

Moving forward with ToxSci

Peters, J. M., Feb 1 2020, In: Toxicological Sciences. 173, 2, p. 227-228 2 p.

Research output: Contribution to journalEditorialpeer-review

Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice

Zhang, L., Rimal, B., Nichols, R. G., Tian, Y., Smith, P. B., Hatzakis, E., Chang, S. C., Butenhoff, J. L., Peters, J. M. & Patterson, A. D., Feb 15 2020, In: Toxicology. 431, 152365.

Research output: Contribution to journalArticlepeer-review

Interplay Between the Host, the Human Microbiome, and Drug Metabolism

Nichols, R. G., Peters, J. M. & Patterson, A. D., Jun 11 2019, In: Human genomics. 13, 1, 1 p.

Research output: Contribution to journalReview articlepeer-review

Continuing a Legacy: Adapting to Ensure the Bright Future of ToxSci

Peters, J. M., Jul 1 2019, In: Toxicological Sciences. 170, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorialpeer-review

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

Peters, J. M., Kim, D. J., Bility, M. T., Borland, M. G., Zhu, B. & Gonzalez, F. J., Sep 2019, In: Molecular Carcinogenesis. 58, 9, p. 1612-1622 11 p.

Research output: Contribution to journalArticlepeer-review

Unraveling the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) expression in colon carcinogenesis

Peters, J. M., Walter, V., Patterson, A. D. & Gonzalez, F. J., Dec 1 2019, In: npj Precision Oncology. 3, 1, 26.

Research output: Contribution to journalReview articlepeer-review