Research Summary
Studies the role of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology and carcinogenesis, with a particular interest in epithelial and liver cancer. He aims to identify new molecules/proteins that can be targeted with existing approaches to improve the efficacy of chemoprevention and chemotherapy. His studies may allow for the development of dietary formulations of agricultural products that will improve human and animal health and prevent serious diseases.
In the News
Research Keywords
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Recent Publications
Chlorpyrifos modulates the mouse gut microbiota and metabolic activity
Nichols, R. G., Rimal, B., Hao, F., Peters, J. M., Davenport, E. R. & Patterson, A. D., Oct 2024, In: Environment international. 192, 109022.Research output: Contribution to journal › Article › peer-review
Thank You, ToxSci 2024 Reviewers
Peters, J. M., Dec 1 2024, In: Toxicological Sciences. 202, 2, p. 153-156 4 p.Research output: Contribution to journal › Editorial › peer-review
2022-2023 Toxicological Sciences: Paper of the Year
Will, Y. & Peters, J. M., Mar 1 2024, In: Toxicological Sciences. 198, 1, p. 2-3 2 p.Research output: Contribution to journal › Editorial › peer-review
Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation
Yokoyama, S., Koo, I., Aibara, D., Tian, Y., Murray, I. A., Collins, S. L., Coslo, D. M., Kono, M., Peters, J. M., Proia, R. L., Gonzalez, F. J., Perdew, G. H. & Patterson, A. D., Oct 28 2024, In: Advanced Science. 11, 40, 2400794.Research output: Contribution to journal › Article › peer-review
Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) in Keratinocytes by Endogenous Fatty Acids
Zhu, B., Zhu, X., Borland, M. G., Ralph, D. H., Chiaro, C. R., Krausz, K. W., Ntambi, J. M., Glick, A. B., Patterson, A. D., Perdew, G. H., Gonzalez, F. J. & Peters, J. M., Jun 2024, In: Biomolecules. 14, 6, 606.Research output: Contribution to journal › Article › peer-review
2021-2022 Toxicological Sciences paper of the year
Guo, L. & Peters, J. M., Mar 1 2023, In: Toxicological Sciences. 192, 1, p. 1-2 2 p.Research output: Contribution to journal › Editorial › peer-review
Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice
Zhu, X., Liu, Q., Patterson, A. D., Sharma, A. K., Amin, S. G., Cohen, S. M., Gonzalez, F. J. & Peters, J. M., Aug 2023, In: Metabolites. 13, 8, 936.Research output: Contribution to journal › Article › peer-review
Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells
Hirao-Suzuki, M., Takayuki, K., Takiguchi, M., Peters, J. M. & Takeda, S., Nov 30 2022, In: Archives of Biochemistry and Biophysics. 731, 109428.Research output: Contribution to journal › Article › peer-review
2020-2021 Toxicological Sciences Paper of the Year
States, J. C. & Peters, J. M., Mar 28 2022, In: Toxicological sciences : an official journal of the Society of Toxicology. 186, 2, p. 177-178 2 p.Research output: Contribution to journal › Editorial › peer-review
The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice
Su, S., Billy, L. J., Chang, S., Gonzalez, F. J., Patterson, A. D. & Peters, J. M., Jan 15 2022, In: Toxicology. 465, 153056.Research output: Contribution to journal › Article › peer-review
Current Challenges and Recent Developments in Mass Spectrometry-Based Metabolomics
Collins, S. L., Koo, I., Peters, J. M., Smith, P. B. & Patterson, A. D., 2021, In: Annual Review of Analytical Chemistry. 14, p. 467-487 21 p.Research output: Contribution to journal › Review article › peer-review
Diminished Hepatocarcinogenesis by a Potent, High-Affinity Human PPARα Agonist in PPARA-Humanized Mice
Foreman, J. E., Koga, T., Kosyk, O., Kang, B. H., Zhu, X., Cohen, S. M., Billy, L. J., Sharma, A. K., Amin, S., Gonzalez, F. J., Rusyn, I. & Peters, J. M., Sep 1 2021, In: Toxicological Sciences. 183, 1, p. 70-80 11 p.Research output: Contribution to journal › Article › peer-review
Species Differences between Mouse and Human PPARα in Modulating the Hepatocarcinogenic Effects of Perinatal Exposure to a High-Affinity Human PPARα Agonist in Mice
Foreman, J. E., Koga, T., Kosyk, O., Kang, B. H., Zhu, X., Cohen, S. M., Billy, L. J., Sharma, A. K., Amin, S., Gonzalez, F. J., Rusyn, I. & Peters, J. M., Sep 1 2021, In: Toxicological Sciences. 183, 1, p. 81-92 12 p.Research output: Contribution to journal › Article › peer-review
Targeting peroxisome proliferator-activated receptor-β/δ (pparβ/δ) for the treatment or prevention of alcoholic liver disease
Koga, T. & Peters, J. M., Nov 2021, In: Biological and Pharmaceutical Bulletin. 44, 11, p. 1598-1606 9 p.Research output: Contribution to journal › Review article › peer-review
Change is Good: What is New for ToxSci?
Peters, J. M., Jan 1 2020, In: Toxicological Sciences. 173, 1, p. 1-2 2 p.Research output: Contribution to journal › Editorial › peer-review