Jason Rasgon

Affiliate Researcher
Titles and Affiliations
Professor, Entomology

Research Summary

Vector arthropods and the pathogens they transmit, with emphasis on release of genetically-modified mosquitoes for disease control, pathogen transmission dynamics and bioterrorism issues. Specifically, he studies how natural genetic variation in wild vector populations conditions phenotypic variation in pathogen transmission and how natural genetic variation in wild vector populations can be artificially altered to have a directed effect on pathogen transmission dynamics.

In the News

Research Keywords

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Recent Publications

Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods

Holmes, C. J., Chakraborty, S., Ajayi, O. M., Uhran, M. R., Frigard, R., Stacey, C. L., Susanto, E. E., Chen, S. C., Rasgon, J. L., DeGennaro, M., Xiao, Y. & Benoit, J. B., Feb 21 2025, In: iScience. 28, 2, 111760.

Research output: Contribution to journalArticlepeer-review

An Overview of Zika Virus and Zika Virus Induced Neuropathies

Wahaab, A., Mustafa, B. E., Hameed, M., Batool, H., Tran Nguyen Minh, H., Tawaab, A., Shoaib, A., Wei, J. & Rasgon, J. L., Jan 2025, In: International journal of molecular sciences. 26, 1, 47.

Research output: Contribution to journalReview articlepeer-review

Variable effects of transient Wolbachia infections on alphaviruses in Aedes aegypti

Dodson, B. L., Pujhari, S., Brustolin, M., Metz, H. C. & Rasgon, J. L., Nov 2024, In: PLoS neglected tropical diseases. 2024-November, e0012633.

Research output: Contribution to journalArticlepeer-review

Eilat virus (EILV) causes superinfection exclusion against West Nile virus (WNV) in a strain-specific manner in Culex tarsalis mosquitoes

Joseph, R. E., Bozic, J., Werling, K. L., Krizek, R. S., Urakova, N. & Rasgon, J. L., 2024, In: Journal of General Virology. 105, 8

Research output: Contribution to journalArticlepeer-review

Gene Editing in the Chagas Disease Vector Rhodnius prolixus by Cas9-Mediated ReMOT Control

Lima, L., Berni, M., Mota, J., Bressan, D., Julio, A., Cavalcante, R., Macias, V., Li, Z., Rasgon, J. L., Bier, E. & Araujo, H., Apr 1 2024, In: CRISPR Journal. 7, 2, p. 88-99 12 p.

Research output: Contribution to journalArticlepeer-review

Corrigendum: A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons

Ma, Q., Srivastav, S. P., Gamez, S., Dayama, G., Feitosa-Suntheimer, F., Patterson, E. I., Johnson, R. M., Matson, E. M., Gold, A. S., Brackney, D. E., Connor, J. H., Colpitts, T. M., Hughes, G. L., Rasgon, J. L., Nolan, T., Akbari, O. S. & Lau, N. C., Feb 7 2024, In: Genome research. 34, 1, p. 160 1 p.

Research output: Contribution to journalComment/debatepeer-review

Precision-guided tools for malaria control

Rasgon, J. L., Aug 6 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 32, e2411587121.

Research output: Contribution to journalComment/debatepeer-review

Microbiomes of Two Pest Fly Species of Pennsylvania Mushroom Houses

Sakamoto, J. M., Shikano, I. & Rasgon, J. L., Jul 2024, In: Insects. 15, 7, 525.

Research output: Contribution to journalArticlepeer-review

Temperature affects viral kinetics and vectorial capacity of Aedes aegypti mosquitoes co-infected with Mayaro and Dengue viruses

Terradas, G., Manzano-Alvarez, J., Vanalli, C., Werling, K., Cattadori, I. M. & Rasgon, J. L., Dec 2024, In: Parasites and Vectors. 17, 1, 73.

Research output: Contribution to journalArticlepeer-review

Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes

Urakova, N., Joseph, R. E., Huntsinger, A., Macias, V. M., Jones, M. J., Sigle, L. T., Li, M., Akbari, O. S., Xi, Z., Lymperopoulos, K., Sayre, R. T., McGraw, E. A. & Rasgon, J. L., Aug 2024, In: Insect Molecular Biology. 33, 4, p. 362-371 10 p.

Research output: Contribution to journalArticlepeer-review

NS2B-D55E and NS2B-E65D Variations Are Responsible for Differences in NS2B-NS3 Protease Activities Between Japanese Encephalitis Virus Genotype I and III in Fluorogenic Peptide Model

Wahaab, A., Zhang, Y., Liu, K., Rasgon, J. L., Kang, L., Hameed, M., Li, C., Anwar, M. N., Zhang, Y., Shoaib, A., Li, B., Qiu, Y., Wei, J. & Ma, Z., Dec 2024, In: International journal of molecular sciences. 25, 23, 12680.

Research output: Contribution to journalArticlepeer-review

Identification of MicroRNAs in the West Nile Virus Vector Culex tarsalis (Diptera: Culicidae)

Asad, S., Mehdi, A. M., Pujhari, S., Rückert, C., Ebel, G. D. & Rasgon, J. L., Mar 1 2023, In: Journal of medical entomology. 60, 2, p. 282-293 12 p.

Research output: Contribution to journalArticlepeer-review

In Vitro and In Vivo Coinfection and Superinfection Dynamics of Mayaro and Zika Viruses in Mosquito and Vertebrate Backgrounds

Brustolin, M., Pujhari, S., Terradas, G., Werling, K., Asad, S., Metz, H. C., Henderson, C. A., Kim, D. & Rasgon, J. L., Jan 2023, In: Journal of virology. 97, 1

Research output: Contribution to journalArticlepeer-review

Novel genome sequences and evolutionary dynamics of the North American anopheline species Anopheles freeborni, Anopheles crucians, Anopheles quadrimaculatus, and Anopheles albimanus

Henderson, C., Kemirembe, K., McKeand, S., Bergey, C. & Rasgon, J. L., Jan 2023, In: G3: Genes, Genomes, Genetics. 13, 1, jkac284.

Research output: Contribution to journalArticlepeer-review

Culex tarsalis Is a Competent Host of the Insect-Specific Alphavirus Eilat Virus (EILV)

Joseph, R. E., Urakova, N., Werling, K. L., Metz, H. C., Montanari, K. & Rasgon, J. L., May 2023, In: Journal of virology. 97, 5

Research output: Contribution to journalArticlepeer-review