Jason Rasgon

IEE Faculty Member
Titles and Affiliations
Professor, Entomology

Research Summary

Vector arthropods and the pathogens they transmit, with emphasis on release of genetically-modified mosquitoes for disease control, pathogen transmission dynamics and bioterrorism issues. Specifically, he studies how natural genetic variation in wild vector populations conditions phenotypic variation in pathogen transmission and how natural genetic variation in wild vector populations can be artificially altered to have a directed effect on pathogen transmission dynamics.

In the News

Research Keywords

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Recent Publications

Gene Editing in the Chagas Disease Vector Rhodnius prolixus by Cas9-Mediated ReMOT Control

Lima, L., Berni, M., Mota, J., Bressan, D., Julio, A., Cavalcante, R., Macias, V., Li, Z., Rasgon, J. L., Bier, E. & Araujo, H., Apr 1 2024, In: CRISPR Journal. 7, 2, p. 88-99 12 p.

Research output: Contribution to journalArticlepeer-review

Corrigendum: A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons

Ma, Q., Srivastav, S. P., Gamez, S., Dayama, G., Feitosa-Suntheimer, F., Patterson, E. I., Johnson, R. M., Matson, E. M., Gold, A. S., Brackney, D. E., Connor, J. H., Colpitts, T. M., Hughes, G. L., Rasgon, J. L., Nolan, T., Akbari, O. S. & Lau, N. C., Feb 7 2024, In: Genome research. 34, 1, p. 160 1 p.

Research output: Contribution to journalComment/debatepeer-review

Microbiomes of Two Pest Fly Species of Pennsylvania Mushroom Houses

Sakamoto, J. M., Shikano, I. & Rasgon, J. L., Jul 2024, In: Insects. 15, 7, 525.

Research output: Contribution to journalArticlepeer-review

Temperature affects viral kinetics and vectorial capacity of Aedes aegypti mosquitoes co-infected with Mayaro and Dengue viruses

Terradas, G., Manzano-Alvarez, J., Vanalli, C., Werling, K., Cattadori, I. M. & Rasgon, J. L., Dec 2024, In: Parasites and Vectors. 17, 1, 73.

Research output: Contribution to journalArticlepeer-review

Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes

Urakova, N., Joseph, R. E., Huntsinger, A., Macias, V. M., Jones, M. J., Sigle, L. T., Li, M., Akbari, O. S., Xi, Z., Lymperopoulos, K., Sayre, R. T., McGraw, E. A. & Rasgon, J. L., 2024, (Accepted/In press) In: Insect Molecular Biology.

Research output: Contribution to journalArticlepeer-review

Identification of MicroRNAs in the West Nile Virus Vector Culex tarsalis (Diptera: Culicidae)

Asad, S., Mehdi, A. M., Pujhari, S., Rückert, C., Ebel, G. D. & Rasgon, J. L., Mar 1 2023, In: Journal of medical entomology. 60, 2, p. 282-293 12 p.

Research output: Contribution to journalArticlepeer-review

In Vitro and In Vivo Coinfection and Superinfection Dynamics of Mayaro and Zika Viruses in Mosquito and Vertebrate Backgrounds

Brustolin, M., Pujhari, S., Terradas, G., Werling, K., Asad, S., Metz, H. C., Henderson, C. A., Kim, D. & Rasgon, J. L., Jan 2023, In: Journal of virology. 97, 1

Research output: Contribution to journalArticlepeer-review

Novel genome sequences and evolutionary dynamics of the North American anopheline species Anopheles freeborni, Anopheles crucians, Anopheles quadrimaculatus, and Anopheles albimanus

Henderson, C., Kemirembe, K., McKeand, S., Bergey, C. & Rasgon, J. L., Jan 2023, In: G3: Genes, Genomes, Genetics. 13, 1, jkac284.

Research output: Contribution to journalArticlepeer-review

Culex tarsalis Is a Competent Host of the Insect-Specific Alphavirus Eilat Virus (EILV)

Joseph, R. E., Urakova, N., Werling, K. L., Metz, H. C., Montanari, K. & Rasgon, J. L., May 2023, In: Journal of virology. 97, 5

Research output: Contribution to journalArticlepeer-review

Dehydration stress and Mayaro virus vector competence in Aedes aegypti

Manzano-Alvarez, J., Terradas, G., Holmes, C. J., Benoit, J. B. & Rasgon, J. L., Dec 21 2023, In: Journal of virology. 97, 12, p. e0069523

Research output: Contribution to journalArticlepeer-review

Signatures of adaptive decreased virulence of deformed wing virus in an isolated population of wild honeybees (Apis mellifera)

Ray, A. M., Gordon, E. C., Seeley, T. D., Rasgon, J. L. & Grozinger, C. M., Oct 25 2023, In: Proceedings of the Royal Society B: Biological Sciences. 290, 2009, 20231965.

Research output: Contribution to journalArticlepeer-review

Anopheles albimanus is a Potential Alphavirus Vector in the Americas

Terradas, G., Novelo, M., Metz, H., Brustolin, M. & Rasgon, J. L., Feb 2023, In: American Journal of Tropical Medicine and Hygiene. 108, 2, p. 412-423 12 p.

Research output: Contribution to journalArticlepeer-review

The Development and Expansion of in vivo Germline Editing Technologies in Arthropods: Receptor-Mediated Ovary Transduction of Cargo (ReMOT Control) and Beyond

Terradas, G., Macias, V. M., Peterson, H., Mckeand, S., Krawczyk, G. & Rasgon, J. L., Dec 1 2023, In: Integrative and comparative biology. 63, 6, p. 1550-1563 14 p.

Research output: Contribution to journalArticlepeer-review

Function and evolution of the aquaporin IsAQP1 in the Lyme disease vector Ixodes scapularis

Tsujimoto, H., Metz, H. C., Smith, A. A., Sakamoto, J. M., Pal, U. & Rasgon, J. L., Aug 2023, In: Insect Molecular Biology. 32, 4, p. 329-339 11 p.

Research output: Contribution to journalArticlepeer-review

Transcriptomic and small RNA response to Mayaro virus infection in Anopheles stephensi mosquitoes

Henderson, C., Brustolin, M., Hegde, S., Dayama, G., Lau, N., Hughes, G. L., Bergey, C. & Rasgon, J. L., 2022, In: PLoS neglected tropical diseases. 16, 6, e0010507.

Research output: Contribution to journalArticlepeer-review