Research Summary
Research interests include modeling/optimization of directed evolution protocols for protein engineering, optimization in metabolic engineering and bioinformatics, molecular and product design, and supply chain planning and scheduling.In the News
Research Keywords
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Recent Publications
Quantifying the propagation of parametric uncertainty on flux balance analysis
Dinh, H. V., Sarkar, D. & Maranas, C. D., Jan 2022, In: Metabolic engineering. 69, p. 26-39 14 p.Research output: Contribution to journal › Article › peer-review
Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2
Chen, C., Boorla, V. S., Banerjee, D., Chowdhury, R., Cavener, V. S., Nissly, R. H., Gontu, A., Boyle, N. R., Vandegrift, K., Nair, M. S., Kuchipudi, S. V. & Maranas, C. D., Oct 19 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 42, e2106480118.Research output: Contribution to journal › Article › peer-review
Building kinetic models for metabolic engineering
Foster, C. J., Wang, L., Dinh, H. V., Suthers, P. F. & Maranas, C. D., Feb 2021, In: Current Opinion in Biotechnology. 67, p. 35-41 7 p.Research output: Contribution to journal › Review article › peer-review
A genome-scale metabolic model of anabaena 33047 to guide genetic modifications to overproduce nylon monomers
Hendry, J. I., Dinh, H. V., Sarkar, D., Wang, L., Bandyopadhyay, A., Pakrasi, H. B. & Maranas, C. D., Mar 2021, In: Metabolites. 11, 3, 168.Research output: Contribution to journal › Article › peer-review
Engineering biology approaches for food and nutrient production by cyanobacteria
Liu, D., Liberton, M., Hendry, J. I., Aminian-Dehkordi, J., Maranas, C. D. & Pakrasi, H. B., Feb 2021, In: Current Opinion in Biotechnology. 67, p. 1-6 6 p.Research output: Contribution to journal › Review article › peer-review
Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2
Patiño-Galindo, J. Á., Filip, I., Chowdhury, R., Maranas, C. D., Sorger, P. K., AlQuraishi, M. & Rabadan, R., Dec 2021, In: Genome Medicine. 13, 1, 124.Research output: Contribution to journal › Article › peer-review
Elucidation of trophic interactions in an unusual single-cell nitrogen-fixing symbiosis using metabolic modeling
Sarkar, D., Landa, M., Bandyopadhyay, A., Pakrasi, H. B., Zehr, J. P. & Maranas, C. D., May 2021, In: PLoS computational biology. 17, 5, e1008983.Research output: Contribution to journal › Article › peer-review
Recent advances in constraint and machine learning-based metabolic modeling by leveraging stoichiometric balances, thermodynamic feasibility and kinetic law formalisms
Suthers, P. F., Foster, C. J., Sarkar, D., Wang, L. & Maranas, C. D., Jan 2021, In: Metabolic engineering. 63, p. 13-33 21 p.Research output: Contribution to journal › Article › peer-review
Computationally Prospecting Potential Pathways from Lignin Monomers and Dimers toward Aromatic Compounds
Wang, L. & Maranas, C. D., May 21 2021, In: ACS Synthetic Biology. 10, 5, p. 1064-1076 13 p.Research output: Contribution to journal › Article › peer-review
dGPredictor: Automated fragmentation method for metabolic reaction free energy prediction and de novo pathway design
Wang, L., Upadhyay, V. & Maranas, C. D., Sep 2021, In: PLoS computational biology. 17, 9, e1009448.Research output: Contribution to journal › Article › peer-review