Ashley Shay

Affiliate Researcher
Titles and Affiliations
Assistant Research Professor, Huck Institutes of the Life Sciences

In the News

Research Keywords

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Recent Publications

A newly synthesized 17-epi-NeuroProtectin D1/17-epi-Protectin D1: Authentication and functional regulation of Inflammation-Resolution

Hamidzadeh, K., Westcott, J., Wourms, N., Shay, A. E., Panigrahy, A., Martin, M. J., Nshimiyimana, R. & Serhan, C. N., Sep 2022, In: Biochemical Pharmacology. 203, 115181.

Research output: Contribution to journalArticlepeer-review

Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi

Hopke, A., Lin, T., Scherer, A. K., Shay, A. E., Timmer, K. D., Wilson-Mifsud, B., Mansour, M. K., Serhan, C. N., Irimia, D. & Hurley, B. P., Oct 21 2022, In: iScience. 25, 10, 105226.

Research output: Contribution to journalArticlepeer-review

Periodontal Stem Cells Synthesize Maresin Conjugate in Tissue Regeneration 3

Rakian, A., Rakian, R., Shay, A. E., Serhan, C. N. & Van Dyke, T. E., Sep 2022, In: Journal of Dental Research. 101, 10, p. 1205-1213 9 p.

Research output: Contribution to journalArticlepeer-review

Cysteinyl Maresins Reprogram Macrophages to Protect Mice from Streptococcus pneumoniae after Influenza A Virus Infection

Tavares, L. P., Brüggemann, T. R., Rezende, R. M., Machado, M. G., Cagnina, R. E., Shay, A. E., Garcia, C. C., Nijmeh, J., Teixeira, M. M. & Levy, B. D., Aug 2022, In: mBio. 13, 4

Research output: Contribution to journalArticlepeer-review

Selenium-dependent metabolic reprogramming during inflammation and resolution

Korwar, A. M., Hossain, A., Lee, T. J., Shay, A. E., Basrur, V., Conlon, K., Smith, P. B., Carlson, B. A., Salis, H. M., Patterson, A. D. & Prabhu, K. S., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100410.

Research output: Contribution to journalArticlepeer-review

A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution

Libreros, S., Shay, A. E., Nshimiyimana, R., Fichtner, D., Martin, M. J., Wourms, N. & Serhan, C. N., Feb 10 2021, In: Frontiers in immunology. 11, 631319.

Research output: Contribution to journalArticlepeer-review

Macrophage Selenoproteins Restrict Intracellular Replication of Francisella tularensis and Are Essential for Host Immunity

Markley, R. L., Restori, K. H., Katkere, B., Sumner, S. E., Nicol, M. J., Tyryshkina, A., Nettleford, S. K., Williamson, D. R., Place, D. E., Dewan, K. K., Shay, A. E., Carlson, B. A., Girirajan, S., Prabhu, K. S. & Kirimanjeswara, G. S., Oct 29 2021, In: Frontiers in immunology. 12, 701341.

Research output: Contribution to journalArticlepeer-review

Stereoselective Synthesis and Structural Confirmation of the Specialized Pro-Resolving Mediator Resolvin E4

Reinertsen, A. F., Primdahl, K. G., Shay, A. E., Serhan, C. N., Hansen, T. V. & Aursnes, M., Feb 19 2021, In: Journal of Organic Chemistry. 86, 4, p. 3535-3545 11 p.

Research output: Contribution to journalArticlepeer-review

PCTR1 Enhances Repair and Bacterial Clearance in Skin Wounds

Sansbury, B. E., Li, X., Wong, B., Riley, C. O., Shay, A. E., Nshimiyimana, R., Petasis, N. A., Serhan, C. N. & Spite, M., Jun 2021, In: American Journal of Pathology. 191, 6, p. 1049-1063 15 p.

Research output: Contribution to journalArticlepeer-review

Human leukocytes selectively convert 4S,5S-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer

Shay, A. E., Nshimiyimana, R., Samuelsson, B., Petasis, N. A., Haeggstrom, J. Z. & Serhan, C. N., Dec 21 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 51, e2116559118.

Research output: Contribution to journalArticlepeer-review

Protectins PCTR1 and PD1 Reduce Viral Load and Lung Inflammation During Respiratory Syncytial Virus Infection in Mice

Walker, K. H., Krishnamoorthy, N., Brüggemann, T. R., Shay, A. E., Serhan, C. N. & Levy, B. D., Aug 19 2021, In: Frontiers in immunology. 12, 704427.

Research output: Contribution to journalArticlepeer-review

Biosynthetic metabolomes of cysteinyl-containing immunoresolvents

Jouvene, C. C., Shay, A. E., Soens, M. A., Norris, P. C., Haeggström, J. Z. & Serhan, C. N., Dec 2019, In: FASEB Journal. 33, 12, p. 13794-13807 14 p.

Research output: Contribution to journalArticlepeer-review

Selenoproteome Identification in Inflamed Murine Primary Bone Marrow-Derived Macrophages by Nano-LC Orbitrap Fusion Tribrid Mass Spectrometry

Korwar, A. M., Shay, A. E., Basrur, V., Conlon, K. & Prabhu, K. S., Jul 15 2019, In: Journal of the American Society for Mass Spectrometry. 30, 7, p. 1276-1283 8 p.

Research output: Contribution to journalArticlepeer-review

IL-4 up-regulates cyclooxygenase-1 expression in macrophages

Shay, A. E., Diwakar, B. T., Guan, B. J., Narayan, V., Urban, J. F. & Prabhu, K. S., Sep 1 2017, In: Journal of Biological Chemistry. 292, 35, p. 14544-14555 12 p.

Research output: Contribution to journalArticlepeer-review

Selenoprotein expression in macrophages is critical for optimal clearance of parasitic helminth Nippostrongylus brasiliensis

Nelson, S. M., Shay, A. E., James, J. L., Carlson, B. A., Urban, J. F. & Prabhu, K. S., Feb 5 2016, In: Journal of Biological Chemistry. 291, 6, p. 2787-2798 12 p.

Research output: Contribution to journalArticlepeer-review