Andrew Zydney
Research Summary
Current research activities are focused in three distinct areas: artificial organs, bioseparations and membrane processes with the goal is of developing a more fundamental understanding of the factors governing the behavior of these processes, including t
In the News
Research Keywords
These keywords and phrases come from the publications and other research output of this person. See other researchers related to these topics by clicking on any keyword.
Projects
Recent Publications
Hydrogenation Kinetics Study: Precise Control of C=C Bonds in Polyisoprene (PI)-Containing Block Copolymers via Diimide Hydrogenation
Caspari Thiele, L. F., Kim, Y., Roberts, C. A., Goel, S., Zydney, A. L., Colby, R. H., Kelkar, M. S., Beuscher, U. & Oh, H. J., Jun 12 2026, In: ACS Applied Polymer Materials. 8, 11, p. 8832-8844 13 p.Research output: Contribution to journal › Article › peer-review
Development of batch and continuous diafiltration processes for effective purification of AAV clarified cell lysate
Chaubal, A. S., Zahn, A. J., Yehl, C. J., Ahmadimashhadi, M., Nawar, H., Carbone, L., Wang, L. & Zydney, A. L., Nov 23 2026, In: Separation and Purification Technology. 415, 139898.Research output: Contribution to journal › Article › peer-review
Downstream Process Intensification for AAV Purification by Affinity Chromatography Using Single Pass Tangential Flow Filtration
Chaubal, A. S., Horax, R., Yehl, C. J., Wickramasinghe, S. R., Qian, X., Wang, L. & Zydney, A. L., Jan 2026, In: Biotechnology and bioengineering. 123, 1, p. 174-185 12 p.Research output: Contribution to journal › Article › peer-review
Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions
Chaubal, A. S., Arachchige, A. W., Zahn, A. J., Wickramasinghe, S. R., Qian, X. & Zydney, A. L., Mar 1 2026, In: Biotechnology progress. 42, 2, e70106.Research output: Contribution to journal › Article › peer-review
Affinity membranes in downstream bioprocessing: From chemical design rules to ligand engineering
Gao, P., Smet, M., Dehaen, W., Zydney, A. L. & Yang, X., Jul 5 2026, In: Journal of Chromatography A. 1778, 467022.Research output: Contribution to journal › Review article › peer-review
Viscosity of concentrated mRNA solutions: Implications for downstream processing
Javidanbardan, A., Najafi, F., Wang, Z. & Zydney, A. L., 2026, (Accepted/In press) In: Biotechnology progress.Research output: Contribution to journal › Article › peer-review
A pressure-dependent pore blockage describes both constant pressure and constant flux sterile filtration of nanoemulsions
Kapila, S. & Zydney, A. L., Oct 2026, In: Journal of Membrane Science. 758, 126067.Research output: Contribution to journal › Article › peer-review
Modulating Membrane Surface Properties via Prewetting With Polysorbate 20 to Improve Sterile Filtration of Nanoemulsions
Kapila, S., Osmanski, M. M., Soukup, R. J., Bradley, M. E., Boyd, D. & Zydney, A. L., Jul 2026, In: Biotechnology Journal. 21, 7, e70280.Research output: Contribution to journal › Article › peer-review
Optimizing sterile filtration of nanoemulsions through proper choice of prefilter properties
Kapila, S., Soukup, R. J., Bradley, M. E., Boyd, D. & Zydney, A. L., Jan 1 2026, In: Biotechnology progress. 42, 1, e70087.Research output: Contribution to journal › Article › peer-review
Characterization of Sterilizing-Grade Membranes/Prefilters and Application to mRNA-LNP Process Development
Messerian, K. O., Zverev, A., Kramarczyk, J. F. & Zydney, A. L., Jan 2026, In: Biotechnology and bioengineering. 123, 1, p. 164-173 10 p.Research output: Contribution to journal › Article › peer-review
Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP)
Mohammadzadehmarandi, A., Heller, N., Ahmadimashhadi, M., Petrone, J., Marchand, N., Darvishmanesh, S., Zhang, K., Menegatti, S. & Zydney, A. L., 2026, (Accepted/In press) In: Biotechnology progress.Research output: Contribution to journal › Article › peer-review
Impact of membrane imprinting on fluid flow in spacer-filled ultrafiltration cassettes: Computational fluid dynamics analysis
Najafi, F., Hersey, J., Carbrello, C., Zou, Y., Steen, J. & Zydney, A. L., Aug 2026, In: Journal of Membrane Science. 756, 125793.Research output: Contribution to journal › Article › peer-review
Mass transfer characteristics of vibration assisted protein ultrafiltration
Piash, K. P. S., Wang, Z., MacElroy, C., Jing, D. M. & Zydney, A. L., May 2026, In: Journal of Membrane Science. 748, 125367.Research output: Contribution to journal › Article › peer-review
The hidden half of lipid nanoparticle manufacturing: Downstream processing
Sagmeister, P., Devos, C., Udepurkar, A., Schwenger, A., Webb, C., McDonald, A., Berry, M., Zydney, A. L., Braatz, R. D. & Myerson, A. S., Sep 10 2026, In: Journal of Controlled Release. 397, 115189.Research output: Contribution to journal › Review article › peer-review
Enhancing forward osmosis for concentrating biotherapeutics using structurally optimized membranes and macromolecular draw solutes
Tangry, V., Thomas, M., Heller, N. & Zydney, A. L., Sep 2026, In: Journal of Membrane Science. 757, 125937.Research output: Contribution to journal › Article › peer-review
