Andrew Zydney
Research Summary
Current research activities are focused in three distinct areas: artificial organs, bioseparations and membrane processes with the goal is of developing a more fundamental understanding of the factors governing the behavior of these processes, including t
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Research Keywords
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Projects
Recent Publications
Hydrogenation Kinetics Study: Precise Control of C=C Bonds in Polyisoprene (PI)-Containing Block Copolymers via Diimide Hydrogenation
Caspari Thiele, L. F., Kim, Y., Roberts, C. A., Goel, S., Zydney, A. L., Colby, R. H., Kelkar, M. S., Beuscher, U. & Oh, H. J., Jun 12 2026, In: ACS Applied Polymer Materials. 8, 11, p. 8832-8844 13 p.Research output: Contribution to journal › Article › peer-review
Downstream Process Intensification for AAV Purification by Affinity Chromatography Using Single Pass Tangential Flow Filtration
Chaubal, A. S., Horax, R., Yehl, C. J., Wickramasinghe, S. R., Qian, X., Wang, L. & Zydney, A. L., Jan 2026, In: Biotechnology and bioengineering. 123, 1, p. 174-185 12 p.Research output: Contribution to journal › Article › peer-review
Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions
Chaubal, A. S., Arachchige, A. W., Zahn, A. J., Wickramasinghe, S. R., Qian, X. & Zydney, A. L., Mar 1 2026, In: Biotechnology progress. 42, 2, e70106.Research output: Contribution to journal › Article › peer-review
Affinity membranes in downstream bioprocessing: From chemical design rules to ligand engineering
Gao, P., Smet, M., Dehaen, W., Zydney, A. L. & Yang, X., Jul 5 2026, In: Journal of Chromatography A. 1778, 467022.Research output: Contribution to journal › Review article › peer-review
Viscosity of concentrated mRNA solutions: Implications for downstream processing
Javidanbardan, A., Najafi, F., Wang, Z. & Zydney, A. L., 2026, (Accepted/In press) In: Biotechnology progress.Research output: Contribution to journal › Article › peer-review
Optimizing sterile filtration of nanoemulsions through proper choice of prefilter properties
Kapila, S., Soukup, R. J., Bradley, M. E., Boyd, D. & Zydney, A. L., Jan 1 2026, In: Biotechnology progress. 42, 1, e70087.Research output: Contribution to journal › Article › peer-review
Characterization of Sterilizing-Grade Membranes/Prefilters and Application to mRNA-LNP Process Development
Messerian, K. O., Zverev, A., Kramarczyk, J. F. & Zydney, A. L., Jan 2026, In: Biotechnology and bioengineering. 123, 1, p. 164-173 10 p.Research output: Contribution to journal › Article › peer-review
Impact of membrane imprinting on fluid flow in spacer-filled ultrafiltration cassettes: Computational fluid dynamics analysis
Najafi, F., Hersey, J., Carbrello, C., Zou, Y., Steen, J. & Zydney, A. L., Aug 2026, In: Journal of Membrane Science. 756, 125793.Research output: Contribution to journal › Article › peer-review
Mass transfer characteristics of vibration assisted protein ultrafiltration
Piash, K. P. S., Wang, Z., MacElroy, C., Jing, D. M. & Zydney, A. L., May 2026, In: Journal of Membrane Science. 748, 125367.Research output: Contribution to journal › Article › peer-review
Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification
Wang, Z., Javidanbardan, A., Behboudi, A. & Zydney, A. L., 2026, (Accepted/In press) In: Biotechnology and bioengineering.Research output: Contribution to journal › Article › peer-review
Letter to the Editor – Introduction to the 50th Anniversary Special Issue of the Journal of Membrane Science
Zydney, A. L., Jan 2026, In: Journal of Membrane Science. 737, 124746.Research output: Contribution to journal › Letter › peer-review
Quantitative Analysis of Protein Fouling in Virus Removal Filtration Membranes Through Electron Tomography
Afzal, M. A., Brickey, K. P., Gomez, E. D. & Zydney, A. L., Dec 2025, In: Membranes. 15, 12, 369.Research output: Contribution to journal › Article › peer-review
Enhanced Tangential Flow Filtration of Precipitated Proteins Using Screened Membrane Cassettes
Badinger, Z., Behboudi, A. & Zydney, A. L., Aug 2025, In: Membranes. 15, 8, 245.Research output: Contribution to journal › Article › peer-review
Development of charged membranes for the ultrafiltration of siRNA
Banik, I., Qian, K. K., Mason, M. L. & Zydney, A. L., Jan 2025, In: Journal of Membrane Science. 713, 123274.Research output: Contribution to journal › Article › peer-review
Effect of ligand density and properties on membrane charge for enhancing ultrafiltration of siRNA
Banik, I., Mason, M. L., Carter, M., Qian, K. K. & Zydney, A. L., Dec 31 2025, In: Separation and Purification Technology. 379, 134951.Research output: Contribution to journal › Article › peer-review
