Research Summary
Current research activities are focused in three distinct areas: artificial organs, bioseparations and membrane processes with the goal is of developing a more fundamental understanding of the factors governing the behavior of these processes, including t
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Research Keywords
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Projects
Recent Publications
Development of charged membranes for the ultrafiltration of siRNA
Banik, I., Qian, K. K., Mason, M. L. & Zydney, A. L., Jan 2025, In: Journal of Membrane Science. 713, 123274.Research output: Contribution to journal › Article › peer-review
Vibration-assisted ultrafiltration dramatically improves mRNA purification
Behboudi, A., Javidanbardan, A., Wang, Z., Zhou, L. & Zydney, A. L., Aug 14 2025, In: Separation and Purification Technology. 363, 132179.Research output: Contribution to journal › Article › peer-review
Development of a local wall concentration model for the design of single pass tangential flow filtration (SPTFF) systems with viral vector surrogates
Chaubal, A. S., Single, A. J. & Zydney, A. L., Jan 2025, In: Journal of Membrane Science. 713, 123276.Research output: Contribution to journal › Article › peer-review
Detergent/surfactant retention during ultrafiltration in the formulation of biotherapeutics
Chu, L. K., Du, Z., Billups, M., Oh, H. J. & Zydney, A. L., May 1 2025, In: Biotechnology progress. 41, 3, e70011.Research output: Contribution to journal › Article › peer-review
Use of LC-MS to characterize host cell protein removal during depth filtration
Chu, L. K., Borujeni, E. E., Xu, X. & Zydney, A. L., 2025, (Accepted/In press) In: Biotechnology progress.Research output: Contribution to journal › Article › peer-review
Enhancing Virus Filter Performance Through Pretreatment by Membrane Adsorbers
Isu, S., Chen, S. T., Daneshpour, R., Shirataki, H., Strauss, D., Zydney, A. L., Qian, X. & Wickramasinghe, S. R., Jan 2025, In: Membranes. 15, 1, 34.Research output: Contribution to journal › Article › peer-review
Single-pass tangential flow filtration (SPTFF) for continuous mRNA concentration and purification
Javidanbardan, A., Wang, Z., Kostic, A., Behboudi, A. & Zydney, A. L., Mar 2025, In: Journal of Membrane Science. 719, 123730.Research output: Contribution to journal › Article › peer-review
Flux and fouling behavior during constant pressure sterile filtration of nanoemulsions
Kapila, S., Soukup, R. J., Bradley, M. E. & Zydney, A. L., Jan 2025, In: Journal of Membrane Science. 713, 123370.Research output: Contribution to journal › Article › peer-review
Perspectives on sterile filter performance through insights obtained by membrane characterization methods
Kapila, S., Messerian, K. O. & Zydney, A. L., Jun 2025, In: Journal of Membrane Science. 728, 124130.Research output: Contribution to journal › Review article › peer-review
Modeling transitional fouling mechanisms for mRNA-lipid nanoparticles during sterile filtration
Messerian, K. O., Zverev, A., Kramarczyk, J. F. & Zydney, A. L., Sep 2025, In: Journal of Membrane Science. 733, 124278.Research output: Contribution to journal › Article › peer-review
Integration of Single Pass Tangential Flow Filtration and High Performance Countercurrent Membrane Purification for Intensification of Monoclonal Antibody Processing
Minervini, M., Mohammadzadehmarandi, A., Behboudi, A., Oppenheim, S. F. & Zydney, A. L., 2025, (Accepted/In press) In: Biotechnology and bioengineering.Research output: Contribution to journal › Article › peer-review
Enhancing the Performance of Tangential Flow Microfiltration for Bioreactor Clarification
Mostafavi, A. H., Chu, L. K., Qian, X., Smelko, J. P., Zhang, D., Zydney, A. & Wickramasinghe, S. R., Mar 2025, In: Membranes. 15, 3, 78.Research output: Contribution to journal › Article › peer-review
The application of forward osmosis for producing highly concentrated biotherapeutics
Tangry, V., Haddad, W., Behboudi, A. & Zydney, A. L., Apr 2025, In: Journal of Membrane Science. 721, 123839.Research output: Contribution to journal › Article › peer-review
Single particle tracking reveals through-membrane diffusion of bacteriophage during process disruption of virus filtration
Wyllie, I., Afzal, M. A., Shi, A., Zydney, A. L. & Schwartz, D. K., Jan 2025, In: Journal of Membrane Science. 713, 123380.Research output: Contribution to journal › Article › peer-review
Comparative Analysis of the Impact of Protein on Virus Retention for Different Virus Removal Filters
Afzal, M. A., Peles, J. & Zydney, A. L., Jul 2024, In: Membranes. 14, 7, 158.Research output: Contribution to journal › Article › peer-review