Introduction to Multi-angle Light Scattering: Theory and Applications

Date and Time
Presenters
Will Penny

Abstract:
Multi-angle light scattering (MALS) is an excellent technique for non-invasive characterization of macromolecules and a wide range of particles in solution. In combination with separation by size-exclusion chromatography (SEC), MALS enables the determination of molar mass distributions without relying on reference standards, making it invaluable for the analysis of polymers, proteins, and polysaccharides.

In this seminar the theory and technology of MALS will be reviewed, then specific applications in the characterization of polysaccharides, proteins, and polymers will be presented.

Bio:
Will Penny, PhD
Will has been an Application Scientist at Wyatt Technology for approximately 2.5 years and provides application support for multi-angle light scattering, dynamic light scattering, and field flow fractionation instrumentation. Prior to his time at Wyatt Technology, Will completed his PhD in Analytical Chemistry at the University of Montana, where he characterized lipid-polymer nanoparticles using dynamic light scattering and capillary electrophoresis.