Josephine Wee's research aims to understand the role of fungi (yeast and mold) and their contribution to food safety, quality, and sustainability. She uses genomics and molecular biology approaches spanning diverse food and agriculture ecosystems to prevent spoilage and food waste, enhance food quality, and create a sustainable food system.
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Projects
Recent Publications
Sourdough starter culture microbiomes influence physical and chemical properties of wheat bread
Clark, C. S., Ohstrom, A., Rolon, M. L., Smith, M., Wolfe, B. E., Wee, J. & Van Buiten, C. B., Mar 2024, In: Journal of Food Science. 89, 3, p. 1414-1427 14 p.Research output: Contribution to journal › Article › peer-review
Evaluation of public submissions to the USDA for labeling of cell-cultured meat in the United States
Failla, M., Hopfer, H. & Wee, J., 2023, In: Frontiers in Nutrition. 10, 1197111.Research output: Contribution to journal › Article › peer-review
Evaluation of Kluyveromyces spp. for conversion of lactose in different types of whey from dairy processing waste into ethanol
Ohstrom, A. M., Buck, A. E., Du, X. & Wee, J., 2023, In: Frontiers in Microbiology. 14, 1208284.Research output: Contribution to journal › Article › peer-review
Dietary Postbiotics Reduce Cytotoxicity and Inflammation Induced by Crystalline Silica in an In Vitro RAW 264.7 Macrophage Model
Du, X., Rodriguez, J. & Wee, J., Mar 1 2022, In: Foods. 11, 6, 877.Research output: Contribution to journal › Article › peer-review
Salivary α-amylase activity and flow rate explain differences in temporal flavor perception in a chewing gum matrix comprising starch-limonene inclusion complexes
Goza, J. L., Ziegler, G. R., Wee, J., Hayes, J. E. & Hopfer, H., Aug 2022, In: Food Research International. 158, 111573.Research output: Contribution to journal › Article › peer-review
Microbial and chemical analysis of non-saccharomyces yeasts from chambourcin hybrid grapes for potential use in winemaking
Feng, C. T., Du, X. & Wee, J., Mar 2021, In: Fermentation. 7, 1, 15.Research output: Contribution to journal › Article › peer-review
Characterization of Microbial Dynamics and Volatile Metabolome Changes During Fermentation of Chambourcin Hybrid Grapes From Two Pennsylvania Regions
Wang, H. L., Hopfer, H., Cockburn, D. W. & Wee, J., Jan 11 2021, In: Frontiers in Microbiology. 11, 614278.Research output: Contribution to journal › Article › peer-review
Understand the genomic diversity and evolution of fungal pathogen Candida glabrata by genome-wide analysis of genetic variations
Guo, X., Zhang, R., Li, Y., Wang, Z., Ishchuk, O. P., Ahmad, K. M., Wee, J., Piskur, J., Shapiro, J. A. & Gu, Z., Apr 1 2020, In: Methods. 176, p. 82-90 9 p.Research output: Contribution to journal › Article › peer-review
Novel insights into global translational regulation through Pumilio family RNA-binding protein Puf3p revealed by ribosomal profiling
Wang, Z., Sun, X., Wee, J., Guo, X. & Gu, Z., Feb 11 2019, In: Current Genetics. 65, 1, p. 201-212 12 p.Research output: Contribution to journal › Article › peer-review
Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal
Wierenga, K. A., Wee, J., Gilley, K. N., Rajasinghe, L. D., Bates, M. A., Gavrilin, M. A., Holian, A. & Pestka, J. J., Sep 20 2019, In: Frontiers in immunology. 10, 2130.Research output: Contribution to journal › Article › peer-review
Activation of aflatoxin biosynthesis alleviates total ROS in Aspergillus parasiticus
Kenne, G. J., Gummadidala, P. M., Omebeyinje, M. H., Mondal, A. M., Bett, D. K., McFadden, S., Bromfield, S., Banaszek, N., Velez-Martinez, M., Mitra, C., Mikell, I., Chatterjee, S., Wee, J. & Chanda, A., Feb 2018, In: Toxins. 10, 2, 57.Research output: Contribution to journal › Article › peer-review
RNA Seq analysis of the role of calcium chloride stress and electron transport in mitochondria for malachite green decolorization by Aspergillus niger
Gomaa, O. M., Selim, N. S., Wee, J. & Linz, J. E., Aug 2017, In: Fungal Genetics and Biology. 105, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
Bioactive compounds in Diospyros mafiensis roots inhibit growth, sporulation and aflatoxin production by Aspergillus flavus and Aspergillus parasiticus
Mmongoyo, J. A., Nair, M. G., Linz, J. E., Wu, F., Mugula, J. K., Dissanayake, A. A., Zhang, C., Day, D. M., Wee, J. M. & Strasburg, G. M., 2017, In: World Mycotoxin Journal. 10, 3, p. 237-248 12 p.Research output: Contribution to journal › Article › peer-review
The fungal bZIP transcription factor AtfB controls virulence-associated processes in Aspergillus parasiticus
Wee, J., Hong, S. Y., Roze, L. V., Day, D. M., Chanda, A. & Linz, J. E., Sep 16 2017, In: Toxins. 9, 9, 287.Research output: Contribution to journal › Article › peer-review
Effects of zinc chelators on aflatoxin production in Aspergillus parasiticus
Wee, J., Day, D. M. & Linz, J. E., Jun 2016, In: Toxins. 8, 6, 171.Research output: Contribution to journal › Article › peer-review